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Tabla 1: Características basales en pacientes con SIRPA vs pacientes sin SIRPA. |
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|
SIRPA (n = 132) |
Sin SIRPA (n = 214) |
p |
|
Edad (años) |
58.76 (48.92-67.91) |
48.86 (39.04-61.53) |
< 0.001 |
|
Sexo (masculino) |
100 (75.76) |
129 (60.28) |
0.003 |
|
SOFA score |
6 (5-9) |
2 (2-3) |
< 0.001 |
|
Comorbilidades |
|
|
|
|
Hipertensión |
79 (61.72) |
164 (77) |
0.003 |
|
Cardiopatía isquémica |
3 (2.34) |
6 (2.86) |
0.776 |
|
ERC |
4 (3.13) |
4 (1.90) |
0.47 |
|
Diabetes |
32 (25.2) |
26 (12.26) |
0.002 |
|
EPOC |
4 (3.17) |
3 (1.42) |
0.275 |
|
Neoplasia |
0 |
0 |
- |
|
Signos vitales |
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Temperatura, oC |
36.5 (36-36.8) |
36.4 (36-37) |
0.631 |
|
Frecuencia cardiaca (lpm) |
81 (75.5-90) |
81 (74-89) |
0.285 |
|
Frecuencia respiratoria (rpm) |
23 (20-30) |
20 (18-22) |
< 0.001 |
|
TAM, mmHg |
86.16 (79.5-90) |
86.66 (81.66-93) |
0.077 |
|
SpO2/FiO2 ratio |
125 (84-165) |
227.5 (215-240) |
< 0.001 |
|
Exámenes de laboratorio |
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Leucocitos, ×109 por L |
8.8 (6.2-13.05) |
6.65 (5.2-8.7) |
< 0.001 |
|
Linfocitos, ×109 por L |
0.915 (0.61-1.19) |
1.065 (0.83-1.52) |
< 0.001 |
|
Plaquetas, ×109 por L |
215 (159-276) |
217 (172-289) |
0.406 |
|
Hemoglobina, g/L |
14.8 (13.65-15.95) |
14.8 (13.6-16.2) |
0.672 |
|
PCR ultrasensible, mg/L |
17.87 (9.08-30.885) |
6.91 (2.58-13.87) |
< 0.001 |
|
Procalcitonina, ng/mL |
0.365 (0.13-1) |
0.11 (0.06-0.22) |
< 0.001 |
|
IL-6, pg/mL |
143 (75.1-259.5) |
43.25 (18.9-81.2) |
< 0.001 |
|
IL-6/linfocitos |
157 (74.5-323.5) |
38 (16-79) |
< 0.001 |
|
Dímero-D, μg/mL |
1046 (599.5-1720.5) |
719.5 (452-1140) |
< 0.001 |
|
Lactato deshidrogenasa, U/L |
369.5 (288-439) |
260 (205-322) |
< 0.001 |
|
Creatinina, mg/L |
0.95 (0.79-1.18) |
0.84 (0.72-1.03) |
< 0.001 |
|
Falla orgánica |
|
|
|
|
Choque séptico |
14 (10.61) |
1 (0.47) |
< 0.001 |
|
LRA |
50 (37.88) |
33 (15.42) |
< 0.001 |
|
Días de hospitalización |
18 (14-24) |
7 (5-9) |
<0.001 |
|
Muerte a 30 días |
24 (18.6) |
1 (0.47) |
< 0.001 |
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SOFA = Sequential Organ Failure Assessment; EPOC = enfermedad pulmonar obstructiva crónica; TAM = presión arterial media; SpO2/FiO2 ratio = relación entre saturación de oxígeno y fracción inspirada de oxígeno; IL-6 = interleucina-6; SIRA = síndrome de insuficiencia respiratoria aguda. |
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