Annex 2: Interpretative reading of the antibiograms obtained in this study. |
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Microorganisms |
Interpretative pattern |
Interpretative reading |
Staphylococcus aureus |
M.S.S.A |
Methicillin-sensitive S. aureus |
M.R.S.A community- phenotype |
Methicillin-resistant S. aureus; clindamycin, trimethoprim/sulfamethoxazole and gentamicin sensitive |
|
M.R.S.A hospital- associated |
Methicillin-resistant S. aureus, clindamycin, trimethoprim/sulfamethoxazole and gentamicin: vancomycin sensitve |
|
V.I.S.A |
S. aureus with intermediate susceptibility to vancomycin. Confirmatory test are required |
|
V.R.S.A |
Vancomycin-resistant S. aureus. Confirmatory test are required |
|
Enterococcus |
A.S.E. |
Ampicillin-sensitive Enterococcus |
A.R.E |
Ampicillin-resistant and vancomycin-sensitive Enterococcus |
|
V.R.E. |
Vancomycin-resistant Enterococcus |
|
Streptococcus |
P.S.S. |
Penicillin-sensitive Streptococcus |
P.I.S |
Streptococcus with intermediate susceptibility to penicillin; ceftriaxone and vancomycin sensitive |
|
P.R.S |
Penicillin-resistant Streptococcus; ceftriaxone and vancomycin sensitive |
|
C.R.S |
Ceftriaxone-resistant Streptococcus, vancomycin-sensitive |
|
Enterobacteriaceae |
Pansensitive EB |
Pansensitive enterobacteria (K. pneumoniae can be naturally resistant to ampicillin) |
Penicillinase- producing EB |
Penicillinase-producing enterobacteria: |
|
Low level penicillinase: resistant to ampicillin, piperacillin, ampicillin-sulbactam, first and second generation cephalosporins |
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High level penicillinase: resistant to ampicillin, piperacillin, ampicillin-sulbactam, piperacilli-tazobactam, first and second generation cephalosporins |
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AmpC EB |
AmpC positive Enterobacteriaceae (resistant to first, second and third generatrion cephalosporins and cefoxitin-resistant) |
|
ESBL producing EB |
Extended-spectrum beta-lactamase-producing Enterobacteriaceae (resistant to first, second, third and fourth generation cephalosporins, resistant to aztreonam, can be cefoxitin-resistant or cefoxitin-sensitive) |
|
CP-EB |
Carbapenemase-producing Enterobacteriaceae (resistant to carbapenems: three or more carbapenems, including ertapenem, can be ESBL producing EB). Confirmatory test are required |
|
MDR-EB |
Multidrug resistance Enterobacteriaceae expressing combined mechanisms of resistance (efflux bomb, porins, etc.) antibiogram interpretative reading by infectologist is required |
|
Nonfermenting Gram-negative Bacilli |
Pansensitive NFGNB |
Pansensitive nonfermenting Gram-negative Bacilli (intrisic resistance to first, second and third generation cephalosporins can exist) |
AmpC NFGNB |
Non-fermenting microorganisms, resistant to first, second and third generation cephalosporins, resistant to cefoxitin, fourth generation cephalosporins-sensitive (cefepime-sensitive) |
|
CP-NFGNB |
Carbapenemase-producing nonfermenting Gram-negative Bacilli: resistant to three or more carbapenems. Confirmatory test are required |
|
MDR- NFGNB |
Multidrug resistance nonfermenting Gram-negative Bacilli expressing combined mechanisms of resistance (efflux bomb, porins, etc.) antibiogram interpretative reading by infectologist is required. |