|
Table 2: Association between hyperlactatemia and clinical, biochemical and outcome variables in patients with acute pulmonary thromboembolism. |
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|
Variable |
Lactate, n (%) |
p |
OR (CI 95%) |
|
|
< 2.0 mmol/L (N = 13) |
> 2.0 mmol/L (N = 17) |
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|
sPESI parameters |
|
|
|
|
|
Male |
4 (30) |
7 (41) |
0.70 |
1.57 (0.3-7.2) |
|
Age > 80 years |
3 (23) |
10 (58) |
0.05 |
4.76 (0.9-23.8) |
|
History of cancer |
2 (15) |
3 (17) |
1.00 |
1.17 (0.1-8.3) |
|
History of chronic cardiopulmonary disease |
8 (61) |
12 (70) |
0.70 |
1.5 (0.3-6.9) |
|
Heart rate > 100 bpm |
9 (69) |
11 (64) |
1.00 |
0.81 (0.1-3.8) |
|
Systolic blood pressure < 100 mmHg |
2 (15) |
12 (70) |
0.003 |
13.2 (2.1-82.5) |
|
Oxygen saturation < 90% |
10 (76) |
14 (82) |
1.00 |
1.4 (0.2-8.4) |
|
Other variables |
|
|
|
|
|
Hypertension |
4 (30) |
10 (58) |
0.12 |
3.2 (0.7-14) |
|
Diabetes mellitus |
4 (30) |
7 (41) |
0.70 |
1.5 (0.3-7.2) |
|
Coronary artery disease |
1 (7) |
1 (5) |
1.00 |
0.7 (0-13) |
|
Outcomes |
|
|
|
|
|
Vasopressor use |
3 (23) |
7 (41) |
0.44 |
2.3 (0.4-11.6) |
|
IMV |
2 (15) |
2 (11) |
1.00 |
0.7 (0-6) |
|
Thrombolysis |
1 (7) |
3 (17) |
0.61 |
2.5 (0.2-28) |
|
Death |
0 |
2 (11) |
0.49 |
– |
|
RVD |
6 (46) |
15 (88) |
0.02 |
8.7 (1.3-54) |
|
BNP |
6 (46) |
12 (70) |
0.17 |
2.8 (0.6-12.6) |
|
TnI |
9 (69) |
10 (58) |
0.70 |
0.6 (0.1-2.9) |
|
Secondary outcome |
11 (84) |
16 (94) |
0.56 |
2.9 (0.2-36) |
|
sPESI = simplified pulmonary embolism severity index; IMV = intermittent mandatory ventilation; RVD = right ventricular dysfunction; BNP = B-type natriuretic peptide; TnI = troponin I; OR = odds ratio. |
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