Table 3: Traumatic and non-traumatic causes of

acute compartment syndrome.

Traumatic causes

Non-traumatic causes

Fractures

of long bones

Intravenous fluids: fluid extravasation; massive fluid resuscitation (e.g., severe thermal burns, sepsis, etc.)

Blunt trauma

(crush injury / crush syndrome)

Hematologic: ischemia-reperfusion injury, thrombosis, bleeding disorders, vascular disease, spontaneous hemorrhage

Burn injuries

Anticoagulation

Constrictive bandages,

splints, or casts

Toxics: animal poisonings and bites; recreational drug injections

Penetrating

trauma

Prolonged limb compression (following severe drug or alcohol intoxication; malposition during surgery)

High-pressure

injection

Revascularization procedures (limb bypass surgery, embolectomy, thrombolysis)

Injury to

vascular structures

Nephrotic syndrome (decreased serum osmolarity)

Group A streptococcus infections of the muscle; systemic inflammatory response syndrome