Table 1: Case series. General characteristics of the patients.

Sex

Age (years)

Background

Clinical

presentation

Findings

in imaging

studies

Lab

findings

Bile culture /

abscess

Treatment

Evolution

Female

92

BADL dependent, T2D, dementia

Painless RHC tumor

Lithiasis cholecystitis, choledocholithiasis, parietal abscess, CCF

Cr 2.91* mg/dl,

CRP 157.7* mg/l,

GPT 13 U/l,

7,800 WBC/µl

L. casei

PD + AB

Multiorgan failure

Died on day six

Male

87

BADL dependent, myasthenia gravis, hypothyroidism, acute cholecystitis

Painless RHC tumor

Cholecystitis lithiasis, parietal abscess, FCC

CRP 1.2 mg/l,

GPT 100* U/L,

Br 0.5 mg/dl,

7,300 WBC/µl

E. coli

PD + AB

Temporary PD maintenance

Favorable

Male

83

BADL independent, HBP, DLP, COPD

Abdominal pain, painful RHC lump

Cholecystitis lithiasis, aerobilia, parietal abscess, cholecysto-colo-parietal fistula

CRP 1.0 mg/dl,

GOT 39 U/l,

GPT 45 U/l,

GGT 92* U/l,

FA 84 U/l,

Br 0.4 mg/dl,

9,600 WBC/µl

E. coli

S. milleri

B. thetaiotaomicron

PD + AB

Definitive: cholecystectomy by laparotomy

Favorable

Female

89

BADL independent

Abdominal pain, vomiting, painful RHC lump

Cholecystitis lithiasis, parietal abscess, CCF

Cr 1.32* mg/dl,

CRP 191.9* mg/l,

GOT 63* U/l,

GPT 42 U/l,

GGT 63* U/l,

FA 141* U/l,

Br 1.1 mg/dl,

16,200* WBC/µl

B. ovatus

PD + CP + AB

Temporary maintenance of the COP

Definitive: laparoscopic cholecystectomy

Favorable

Male

75

BADL independent, history of gastric ulcer surgically operated

Weight loss, irreducible painless lump (laparotomy)

Alithiasic cholecystitis, parietal abscess, CCF

CRP 17.1* mg/l,

GOT 26 U/l,

GPT 11 U/l,

GGT 64* U/l,

FA 130* U/l,

Br 0.2 mg/dl,

7,300 WBC/µl

4 aerobic bacterial species

Mixed anaerobic

flora

DP + AB

Palliative: biliary endoprosthesis, chemotherapy

Favorable

Gallbladder neoplasia E. IV

Died at month 14

BADL = basic activities of daily living.

T2D = type II diabetes mellitus.

RHC = right hypochondrium.

CCF = cholecystocutaneous fistula.

Cr = serum creatinine.

CRP = C-reactive protein.

GPT = serum glutamic pyruvic transaminase.

WBC = leukocytes.

PD = percutaneous drainage.

AB = antibiotic therapy.

HTA = arterial hypertension.

DLP = dyslipidemia.

COPD = chronic obstructive pulmonary disease.

GOT = glutamic oxaloacetic transaminase.

GGT = gamma-glutamyl transferase.

PC = percutaneous cholecystostomy.

* All data are from the review of medical records performed by authors.