Table 2: Recommendations for the use of preoperative antibiotic prophylaxis.

Type of surgery

Recommended prophylaxis

Recommended prophylaxis in case of allergy to β-lactams

Level of evidence

Laparoscopy:

Elective

(low risk)

None

None

A

Elective

(high risk)

Cephalothin

Ceftriaxone

Clindamycin or vancomycin + aminoglycoside or fluoroquinolone

A

Amoxicillin /

clavulanate

Metronidazole + aminoglycoside or fluoroquinolone

 

Biliary:

Open

procedure

Cephalothin

Ceftriaxone

Clindamycin or vancomycin + aminoglycoside or fluoroquinolone

A

Amoxicillin /

clavulanate

 

 

Gastroduodenal

Cephalothin

Clindamycin or vancomycin + aminoglycoside or fluoroquinolone

A

Intestinal:

With

obstruction

Cephalothin

Clindamycin or vancomycin + aminoglycoside or fluoroquinolone

C

No

obstruction

Cephalothin +

metronidazole

Metronidazole + aminoglycoside or fluoroquinolone

C

Appendiceal*

Cephalothin +

metronidazole

Clindamycin or vancomycin + aminoglycoside or fluoroquinolone

A

 

Metronidazole + aminoglycoside or fluoroquinolone

 

Colorectal

Cephalothin + metronidazole

Clindamycin + aminoglycoside or fluoroquinolone

A

Amoxicillin / clavulanate

Metronidazole + aminoglycoside or fluoroquinolone

 

Ceftriaxone +

metronidazole

 

 

Ertapenem

 

 

* Uncomplicated appendicitis.

Table adapted from: Mexican Institute of Social Security.8