|
Table 3: Bifurcation trials. |
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|
Trial |
Design |
Year |
n |
Scenario |
Material |
|
PEPCAD V62 |
Open-Label, Core Lab, CEC |
2011 |
28 |
DCB in MB and SB + BMS in MB |
BMS, PCB: 3 µg/mm2 iopromide |
|
DEBUIT63 |
1:1:1, Open-Label, Core Lab, CEC |
2012 |
117 |
1. DCB in MB and SB + BMS in MB 2. BMS in MB and POBA in SB 3. PES in MB and POBA in SB |
PES, BMS, PCB 3 µg/mm2 PTX DMSO |
|
BABILON64 |
1:1, Open-Label, Core Lab, CEC |
2014 |
108 |
1. DCB in MB and SB and BMS in MB 2. Provisional T stent with DES |
DES, BMS, PCB 3 µg/mm2 iopromide |
|
DEBSIDE65 |
Open-Label, Core Lab, CEC |
2015 |
50 |
PES in MB and DCB in SB |
PES, PCB 2.5 µg/mm2 BTHC |
|
SARPEDON66 |
Open-Label, CEC |
2015 |
50 |
DES in MB and DCB in SB |
DES, PCB 3 µg/mm2 BTHC |
|
PEPCAD- BIF67 |
1:1, Open-Label, Core Lab, CEC |
2016 |
64 |
DES in MB and 1. POBA in SB 2. DCB in SB |
PCB 3 µg/mm2 iopromide |
|
CEC = clinical events committee. PCB = paclitaxel-coated balloon. MB = main branch. SB = side branch. BMS = bare metal stent. POBA = plain old balloon angioplasty. DES = drug-eluting stent. PES = paclitaxel-eluting stent. BTHC = butyryl-tri-hexyl-citrate. DCB = drug-coated balloon. PTX DMSO = paclitaxel dimethyl sulfoxide. |
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