Table 2: Small vessel disease trials.

Trial

Design

Year

n

Scenario

Material

BASKET 256

1:1,

Open-Label,

Core Lab,

CEC

2018

758

Small

vessel

EES, PES, PCB

3 µg/mm2

iopromide

BELLO57

1:1,

Open-Label,

Core Lab,

CEC

2012

182

Small

vessel

BMS, PES

PEPCAD58

Open-Label,

Core Lab,

CEC

2010

118

Small

vessel

PCB

3 µg/mm2

iopromide,

BMS bailout

PICCOLETO59

1:1,

Open-Label,

CEC

2010

57

Small

vessel

PES, PCB

3 µg/mm2

PTX DMSO

(d(i)m(ethyl)s(ulf)o(xide)

PICCOLETO II60

1:1,

Open-Label,

CEC

2020

214

Small

vessel

EES,

PCB ≈2 µg/mm2

RESTORE61

1:1,

Open-Label,

Core Lab,

CEC

2018

230

Small

vessel

EES,

PCB

3 µg/mm2

iopromide

CEC = clinical events committee.

EES = everolimus-eluting stent.

PES = paclitaxel-eluting stent.

PCB = paclitaxel-coated balloon.

BMS = bare metal stent.

PTX DMSO = paclitaxel dimethyl sulfoxide.