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2020, Number 3

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Cuba y Salud 2020; 15 (3)

SARS-CoV, MERS-CoV and SARS-CoV-2: what is known about these epidemic coronaviruses

Piamo MAJ, García RM

Language: Spanish
References: 91
Page: 64-75
PDF size: 1706.16 Kb.


ABSTRACT

Objetive: organize the information available on the behavior of the three coronaviruses that cause major fatal epidemics: SARSCoV, MERS-CoV and SARS-CoV-2.
Development: The information was collected through a search on PubMed for English Language Publications (90). The keywords: “coronavirus”, “pandemic”, “SARS CoV”, “MERSCoV”, “SARSCoV- 2”, “clinical manifestations”, “fatality rate” and “Diagnosis” in various combinations, in published articles from 2011 to 2020. SARS-CoV, MERS-CoV and SARS-CoV-2 are the causal agents of large epidemics with high rates morbidity and mortality. All three viruses have similarities genomic, clinical and epidemiological; usually manifest with respiratory symptoms that can evolve from the forms mild to severe clinical conditions, with high fatality rates in specific populations.
Conclusions: Since SARS-CoV, MERS-CoV and SARS-CoV-2 are coronavirus, with similar characteristics regarding its genome, epidemiological behavior and clinical manifestations, containment measures and the population and individual treatment of COVID-19 should be assumed from the experiences of the two first epidemics: severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS).


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