2021, Number 1
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Sal Jal 2021; 8 (1)
Seroprevalencia de Virus Herpes Simple Tipo 1 en una muestra poblacional de la Zona Metropolitana de Guadalajara y municipios aledaños
Gamboa-Cañedo EA, Martínez-Limón FJ, Santibañez-Escobar PL, Padilla-Rosas M, Nava-Villalba M
Language: Spanish
References: 25
Page: 26-34
PDF size: 292.63 Kb.
ABSTRACT
Introduction: Due to the diversity of clinical presentations
that Herpes Simplex Virus type 1 (HSV-1) infection
may developing, accurate recording of its incidence, is
complicated; outstanding the fact that in a signifi cant
number of cases the primary infection is subclinical, another
underdiagnosed or undervalued. One approach to determine
the degree of population exposure is via seroprevalence,
knowing this indicator, the specialists and those responsible
for health policies can be guided to consider prevention,
diagnosis and treatment measures.
Objective: To determine
the HSV-1 seroprevalence in a population sample from the
Guadalajara Metropolitan Area (GMA) and to assess whether
positive cases show a correlation with sociodemographic
characteristics.
Methods: Descriptive cross-sectional study,
which 75µL of remnant serum was collect from patients aged
0-80 years, who attended the Clinical Pathology Laboratory
of the Hospital Civil de Guadalajara “Dr. Juan I. Menchaca”.
Subsequently, ELISA assays to detect HSV-1 (IgG), were
performed.
Results: From 133 samples collected, 69% were
women with 72% positive cases in them and 59% in men
group. Seropositivity rises as age increased (Spearman, *p =
.0244). On average, 95% of the subjects older than 30 years
present antibodies against HSV-1. Th e minimum period
registered (0-2 years old) presented 11% seroprevalence.
Regarding occupation, most of subjects evaluated are
housewives (54.02%) with 91.5% of seropositivity. Although
it is not signifi cant, a negative trend between the lowest
degree of studies achieved and a high seropositivity was
observed.
Conclusions: HSV-1 seroprevalence was high
in this GMA population sample (67.66%). Th e research
revealed a trend of infection among vulnerable groups and it
confi rmed that seropositivity increases in adults.
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