Guerrero TP, Garoz FJE, Duany ALF

Language: Spanish
References: 12
Page: 680-689
PDF size: 386.53 Kb.

ABSTRACT

Introduction: hereditary multiple osteochondromatosis, an autosomal dominant entity, characterized by the growth of multiple benign tumors called osteochondromas.
Case presentation: 12-year-old female patient, who comes to the consultation referring to constant pain in the right knee, more accentuated with the gait. PHYSICAL exam SOMA: Increase of volume of right knee towards their outer and inner faces with pain to palpation, it palps hard mass, not movable, of irregular edges. Tumors of similar characteristics are also found in both shoulders and knees.
Discussion: X-rays are performed, observing bone lesions in the proximal metaphysis of both humeruses to right predominance. Exostosis at the level of proximal and distal metaphysis of both femurs, in tibia and bilateral fibula. In the right knee, growth is observed towards the midline of the fibula tumor displacing the proximal metaphysis of the tibia in valgo. Conclusions: Multiple exostosis is raised as a diagnosis.
Surgical treatment was performed tumor excision of the proximal end of the fibula of the right knee and the inner face of the proximal metaphysis of the tibia and biopsy that confirmed the diagnosis.

REFERENCES

1. Santos Guzmán J, Cantú Reyna C, Cano Muñoz AL, Pulido Ayala AK, García A. Osteocondromatosis múltiple hereditaria en una familia. Bol Med Hosp Infant Mex. 2016; 73(2): 111-16.

2. Stieber JR, Dormans JP. Manifestations of Hereditary Multiple Exostoses. J Am Acad Orthop Surg 2005; 13: 110-120.

3. Orgaz Álvarez M, Lorente Jareño ML, Gamero Medina V, Cedeño Poveda MF, Vara Cilla R, Bueno Sánchez A. Osteocondromatosis Múltiple Hereditaria: Más allá del diagnóstico. SERAM 2014; 11(50): 1-39.

4. Carpintero P, del Fresno JA, Carpintero R, Gálvez MJ, Marín MA. Complicaciones de los Osteocondromas. Rev Española de Cirugía Osteoarticular 2009; 237(44): 22-9.

5. Wells M, Birchard Z. A 40-Year-Old Male Presenting with Hereditary Multiple Exostosis: Management and Considerations. Hindawi [Internet]. 2019 [citado 1/5/2020]. Disponible en: https://www.hindawi.com/journals/crior/2019/4793043/

6. Mederos Mesa LR, Ginorio Suárez N, Pineda Folgoso L. Exostosis múltiple hereditaria. MediCiego. 2018; 24(3): 22-7.

7. Eke GK, Omunakwe HE, Echem RC. Hereditary multiple exostoses in a15-year-old boy: A case report and review of literature. Case Report. Niger J Paediatr. 2016; 43(4): 295-298.

8. Sáez Moreno MA, Torres Hidalgo JL, González González F. Manejo de lesiones óseas: osteocodroma. Rev Clin Med Fam. 2017; 10(2): 154-57.

9. Akbaroghli S, Balali M, Kamalidehghan B, Saber S, Aryani O, Yong Meng G, et al. Identification of a new mutation in an Iranian family with hereditary multiple osteochondromas. Ther Clin Risk Manag. 2016; 13: 15-19.

10. Cammarata Scalisi F, Stock F, Avendaño A, Cozar M, Balcells S, Grinberg D. Estudio clínico y molecular en una familia con osteocondromatosis múltiple. Acta Ortop Mex. 2018; 32(2): 108-11.

11. Aedo Martín D, Martínez Álvarez S, Vara Patudo I, Alonso Hernández J. Fusión radiocubital en paciente con osteocondromatosis múltiple hereditaria. Revista Iberoamericana de Cirugía de la Mano. 2017; 45: 40-4.

12. Saint Pierre Contreras G, Bravo Rius E, Valencia Castillo M, Conei Valencia D. Osteocondroma como hallazgo incidental en Úlcera Varicosa Sobreinfectada en miembro inferior. J Health Med SCI. 2018; 4: 5-9.