2020, Number 5
Rev Clin Esc Med 2020; 10 (5)
Rol del Staphylococcus aureus en la patogénesis del Lupus Eritematoso Sistémico
Calderón VG, Casares FD
Language: Spanish
References: 7
Page: 13-17
PDF size: 178.04 Kb.
ABSTRACT
Autoimmune diseases, including Systemic Lupus Erithematosus, bear a complex pathogenesis which encompasses complex reactions between various factors. A series of infectious agents have been associated with the development of the disease, nonetheless there’s no definite culprit for Lupus’ wrongdoings. Staphylococcus aureus’ accountability around immune dysregulation continues to be enigmatic, nevertheless its bacterial superantigen has been correlated with SLE-like inflammation and already-diagnosed individuals colonized by the bacteria express a particular disease phenotype associated with greater cutaneous, renal and articular manifestations, as well as a broader spectrum of antibody seropositivity.REFERENCES