2021, Number 1
SARS-CoV-2 infection in women with severe preeclampsia in a Intensive Care Unit. Prognostic and correlation with viral load
Lozano ZR, Ramos NM, Hernández PJA, Gutiérrez MA, Helguera RC, León JM, Espino SS
Language: Spanish
References: 5
Page: 23-27
PDF size: 191.33 Kb.
ABSTRACT
Objective: To compare the prognosis of women admitted to the intensive care unit of the National Institute of Perinatology for severe preeclampsia and SARS-CoV-2 infection, measuring the correlation between viral load and maternal complications. Material and methods: Study of a cohort of women with pre-eclampsia admitted to an Intensive Care Unit, by non-probabilistic sampling per consecutive case of 105 women in the period from March 1, 2020 to October 15, 2020, for whom a count of platelets, aminotransferases, protein/creatinine ratio in casual urine (mg/dL), urea and creatinine, and demographic data in the first hours of admission. Results: There were no differences in the number of maternal complications between COVID-19-positive women with severe preeclampsia (27.5%) versus COVID-19-negative women (23.6%), p = 0.58. A positive COVID-19 test did not increase the risk of maternal complications OR 1.31 (95% CI, 0.495-3.47). The degree of proteinuria was higher in women with a positive test. Pneumonia associated with COVID-19 was considered in 27.5% of positive women. There was a better correlation between the variables of blood pressure and the AST/ALT ratio in women with pneumonia and viral load. Conclusions: The present study shows that in women with severe preeclampsia treated in the intensive care unit, maternal complications do not increase when there is SARS-CoV-2 infection.REFERENCES