Capote LE

Language: Spanish
References: 9
Page: 137-142
PDF size: 219.95 Kb.

ABSTRACT

Porphyria cutanea tarda (PCT) is a relatively common disease. It is the result of the functional deficiency of an enzyme called uroporphyrinogen decarboxylase. In patients on intermittent periodic hemodialysis, it is described a similar clinical situation called late cutaneous pseudoporphyria. The case of a patient in intermittent periodic hemodialysis for 5 years is presented. The patient has C virus liver disease that develops bullous lesions on the skin exposed to the sun, and had an adequate response to the indicated therapy (based on the restriction of iron use, in a more effective use of erythropoietin, periodic phlebotomies of low volume and protection from solar radiation). The lesions disappeared with the medical measures taken to improve the patient’s quality of life.

REFERENCES

1. Beers MH, Porter RS, Jones TV, Kaplan JL, Berkwits M, editores. El Manual Merk de Diagnóstico y Tratamiento. Madrid: Elsevier; 2007.

2. Enrique de Salamanca R. Capítulo 217. Porfirias. En: Rozman C, Cardellach F, editores. Medicina Interna. 17ma. ed. Barcelona: Elsevier; 2012. p. 1708-15.

3. Muray S, Casanova JM, Marco MP, Claver L, Martin M, Fernández E. Porfiria cutánea tarda, hemodiálisis y hepatopatía VHC. Nefrología. 2002;XXII(6):570-3.

4. Gibson GE, McGinnity E, McGrath P, Carmody M, Walshe J, Donohoe J, et al. Cutaneous abnormalities and metabolic disturbance of porphyrins in patients on maintenance haemodialysis. Clin Exp Dermatol [revista en Internet]. 1997 [citado 14/03/2018];22(3):[aprox. 8p]. Disponible en: Disponible en: https://onlinelibrary.wiley.com/.

5. Labidi J. Porphyria cutanea tarda in a chronic hemodialysis patient. Saudi J Kidney Dis Transpl [revista en Internet]. 2010 [citado 14/03/2018]; . Disponible en: Disponible en: http://www.sjkdt.org/article.asp?issn=13192442;year=2010;volume=21;issue=5;spage=919;epage=922;aulast=Labidi.

6. Massaki M, Pereira FP, Amante H, Alencar ME. Pseudoporphyria induced by dialysis treated with oral N-acetylcysteina. An Bras Dermatol [revista en Internet]. 2011 [citado 14/03/2018];86(2):[aprox. 3p]. Disponible en: Disponible en: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962011000200031&lng=pt&nrm=iso&tlng=en.

7. Bissell DM, Anderson KE, Bonkousky HL. Porphyria. N Engl J Med. 2017;377:862-72.

8. Ruiz JA, Agreda MJ, Gil P, Jaurrieta F, Rivero A. Pseudoporfiria cutánea tarda en hemodiálisis. Nefrología . 1998;XVIII(2):165-67.

9. Frider B, Buonsante ME, Tiscornia J, Alessio A, Pellerano G. Aparición de porfiria cutánea tarda durante el tratamiento con peg-interferón más rivabirina en un paciente con hepatitis C crónica con viremia indetectable. Acta Gastroenterol Latinoam. 2006;36(1):38-41.