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2021, Number 1

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Dermatología Cosmética, Médica y Quirúrgica 2021; 19 (1)

The Microbiome Revolution and Cutaneous Diseases. Review Article

Maza MM, Rivas CMK, García RMT

Language: Spanish
References: 85
Page: 52-63
PDF size: 342.73 Kb.


ABSTRACT

The human body is colonized by a great number and variety of microorganisms which, together with their genomes and interactions with the host, make up what we know as the human microbiome.
In recent years, interest in the role of the human microbiome in the development of different diseases has grown, and the field of dermatology is no exception. Different studies have shown that modifications in the cutaneous and gastrointestinal microbiome play a role in the pathogenesis of different cutaneous diseases. A better characterization of the human microbiome and its interaction with the immune system may allow deeper understanding of these pathologies, and even the opportunity to create new therapeutic modalities.
This review focuses on the most recent knowledge about the gastrointestinal and skin microbiome and their participation in pathogenic mechanisms of different skin conditions, in addition to analyzing the evidence about the therapeutic potential of modifying the microbiome through the use of probiotics and prebiotics in dermatology.


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