2018, Number 2
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Bol Clin Hosp Infant Edo Son 2018; 35 (2)
Administration of intravenous fluids and case fatality rate in children with spotted fever
Martínez-Medina MÁ, Pérez-Jacinto AA
Language: Spanish
References: 21
Page: 92-98
PDF size: 208.23 Kb.
ABSTRACT
The damage to the vascular permeability produced in the Mountain Spotted Fever for Rickettsia Rickettsii (FMRR) leads
to a severe shock state, which must be corrected quickly. However, fluid overload is indicated as a risk of adverse outcomes.
The objective was to find the possible relationship between the fluids administered at the patient’s admission and
the lethality of the disease. Material and Methods: Twenty-eight children with FMRR were studied. The clinical variables
and laboratory results were obtained from the record of each patient. The FMRR was classified according to its severity.
In addition, the amount of fluids administered in the first 24 hours of treatment was obtained. The study group was
divided into fatal and non-fatal cases. Results: The mean volume of fluids administered per ml / m2sc / day in non-fatal
cases was 1,833 ± 708 and in deceased patients 4,056 ± 168 (P = 0.000). As for the group of serious patients, the nonfatal
patients received a total of 1,746 ± 741ml / m2sc / day and the fatal ones were 4,362 ± 1,616 m2sc / day (P ‹0.017).
Conclusion: Fluid administration during the first 24 hours of admission in fatal cases was significantly greater than that
given to nonfatal patients. Fluid overload can contribute to the risk of death in severe cases of FMRR.
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