medigraphic.com
ISSN 1029-3035 (Electronic)

2020, Number 3

<< Back Next >>

Mediciego 2020; 26 (3)

Probability model of death from secondary peritonitis

Elias-Sierra R, Bordelois-Abdo MS, Choo-Ubals T, Elias-Armas KS

Language: Spanish
References: 20
Page: 1-15
PDF size: 578.78 Kb.


ABSTRACT

Introduction: secondary peritonitis are frequent and have a high lethality.
Objective: to corroborate the practical value of the probability model of death from secondary peritonitis, previously validated by specialists.
Methods: a prospective cohort-type epidemiological risk study was carried out in four stages at the Hospital “Dr. Agostinho Netoˮ, in 2016 and 2017. The population was made up of all patients with secondary peritonitis, grouped according to whether they were discharged dead (cases n =18) or alive (controls n =58). The variables most related to the probability that the patient died were specified. The absolute risk of each variable was calculated. The designed model was validated in workshops with specialists and, later, applied in healthcare practice. The ethical precepts were fulfilled.
Results: the absolute risk of the variables most associated with the prognosis of dying were: multi-organ failure (17,8 %), fecaloid peritoneal fluid (7,8 %) and septic shock (7,3 %). All specialists (100,0 %) evaluated the model as adequate, and its application corroborated its level of precision in terms of sensitivity (92,8 % CI 95,0 % 75,0-100,0 p <0,01) and specificity (98,8 % CI 95,0 % 77,8-100.0 p <0,001).
Conclusions: the practical value of the model of probability of death due to secondary peritonitis designed was corroborated, previous validation of its scientific-methodological relevance by specialists.


REFERENCES

  1. Van Ruler O, Boermeester MA. Surgical treatment of secondary peritonitis. A continuing problem. Der Chirurg [Internet]. 2017 [citado 26 Ene 2019];88 Supl 1:[aprox. 8 p]. Disponible en: https://link.springer.com/content/pdf/10.1007/s00104-015-0121-x.pdf

  2. Salamone G, Licari L, Falco N, Augello G, Tutino R, Campanella S, et al. Mannheim Peritonitis Index (MPI) and elderly population: prognostic evaluation in acute secondary peritonitis. G Chir [Internet]. 2016 [citado 26 Ene 2019];37(6):243-9. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5505481/pdf/243-249.pdf

  3. Sharma R, Ranjan V, Jain S, Joshi T, Tyagi A, Chaphekar R. A prospective study evaluating utility of Mannheim peritonitis index in predicting prognosis of perforation peritonitis. J Nat Sci Biol Med [Internet]. 2015 [citado 26 Ene 2019];6 Supl 1:25-32. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4630763/

  4. Rodríguez C, Arce AC, Samaniego C. Peritonitis aguda secundaria. Causas, tratamiento, pronóstico y mortalidad. Rev Cir Parag [Internet]. 2014 [citado 26 Ene 2019];38(1):[aprox. 7 p.]. Disponible en: http://scielo.iics.una.py/pdf/sopaci/v38n1/v38n1a04.pdf

  5. Nakagoe T, Miyata H, Gotoh M, Anazawa T, Baba H, Kimura W, et al. Surgical risk model for acute diffuse peritonitis based on a Japanese nationwide database: an initial report on the surgical and 30-day mortality. Surg Today [Internet]. 2015 [citado 26 Ene 2019];45(10):1233-43. Disponible en: https://link.springer.com/content/pdf/10.1007/s00595-014-1026-x.pdf

  6. Paduszyńska K, Kaczka K, Dworzyńska A, Sieniawsk K, Pomorski L. Evaluating the prognostic value of selected prognostic scales in patients operated on due to peritonitis. Pol Przeglad Chir. 2014;86(9):422-8.

  7. Roque-Pérez L, Roque-Morgado M, Gómez-Mantilla N, Salinas-Batista M, Moyano-Alfonso I, Pérez-Parrado J. Factores pronósticos de mortalidad en pacientes con peritonitis secundaria hospitalizados en la unidad cuidados intensivos. Rev Cub Med Int Emerg. [Internet]. 2016 [citado 26 Ene 2019];15(2):16-33. Disponible en: http://www.revmie.sld.cu/index.php/mie/article/download/138/pdf_8

  8. Suárez-Domínguez R, Mirabal-Elías N, Navarro-Rodríguez Z, Planas-Rodríguez M, Carbonell-Castillo RA. Factores pronósticos de mortalidad por peritonitis secundaria en pacientes ingresados en una unidad de cuidados intensivos. MEDISAN [Internet]. 2016 [citado 26 Ene 2019];20(10):5001-8. Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1029-30192016001000008

  9. Saravanan KV, Alagarsamy KS, Sankar U. prospective study to evaluate the utility of Mannheim peritonitis index in predicting prognosis of perforation peritonitis at our tertiary care centre. Int Surg J [Internet]. Oct 2017 [citado 27 Jul 2018];4(10):3245-8. Disponible en: https://mail.ijsurgery.com/index.php/isj/article/download/1928/1478

  10. Godínez-Vidal AR, García-Vivanco DM, Montero-García PJ, Martínez-Martínez AR, Gutiérrez-Banda CA, Gracida-Mancilla NI. Utilidad del índice SOFA en sepsis abdominal por peritonitis secundaria. Rev Hosp Jua Mex [Internet]. 2018 [citado 26 Ene 2019];85(4):195-200. Disponible en: https://www.researchgate.net/profile/Ansony_Godinez_Vidal/publication/329876932_Utilidad_del_indice_SOFA_en_sepsis_abdominal_por_peritonitis_secundaria/links/5c1f19c992851c22a33fd751/Utilidad-del-indice-SOFA-en-sepsis-abdominal-por-peritonitis-secundaria.pdf

  11. Hernández-Ruiz A, Vinent-Llorente JA, Delgado-Fernández RI, Castillo-Cuello JJ. Factores que influyen en la mortalidad en los pacientes graves con cirugía abdominal. Rev. Cub. Cir. [Internet], 2014 [citado 26 Ene 2019];53(2):134-44. Disponible en: http://scielo.sld.cu/pdf/cir/v53n2/cir03214.pdf

  12. Rodríguez-Álvarez ET, González-Aguilera JC, Cabrera-Lavernia JO, Algas-Hechavarría LA. Factores pronósticos de fallo orgánico y muerte en pacientes con peritonitis difusa secundaria. Rev Cub Med Int Emerg [Internet]. 2018 [citado 26 Ene 2019];17(4):1-18. Disponible en: http://www.revmie.sld.cu/index.php/mie/article/download/424/601

  13. Asociación Médica Mundial. Declaración de Helsinki de la AMM. Principios éticos para las investigaciones médicas en seres humanos. Ratificada en la 64ª Asamblea General, Fortaleza, Brasil, octubre 2013. Helsinki: 18ª Asamblea Mundial; 1964 [citado 26 Ene 2019]. Disponible en: http://www.anmat.gov.ar/comunicados/HELSINSKI_2013.pdf

  14. Ghosh PS, Mukherjee R, Sarkar S, Halder SK, Dhar D. Epidemiology of secondary peritonitis: analysis of 545 cases. Int J Sci Stud [Internet]. 2016 [citado 26 Ene 2019];3(12):83-8. Disponible en: https://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.1072.5701&rep=rep1&type=pdf

  15. Launey Y, Duteurtre B, Larmet R, Nesseler N, Tawa A, Mallédant Y, et al. Risk factors for mortality in postoperative peritonitis in critically ill patient. World J Crit Care Med [Internet]. 2017 [citado 26 Ene 2019];6(1):48-55. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5295169/pdf/WJCCM-6-48.pdf

  16. Ballus J, López-Delgado JC, Sabater Riera J, Pérez Fernández XL, Betbese AJ, Roncal JA. Surgical site infection in critically ill patients with secondary and tertiary peritonitis: epidemiology, microbiology and influence in outcomes. BMC Infect Dis [Internet]. 2015 [citado 26 Ene 2019];15:304-10. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4520265/pdf/12879_2015_Article_1050.pdf

  17. Ayandipo OO, Afuwape OO, Irabor DO Abdurrazzaaq AI, Nwafulum NA. Outcome of laparotomy for peritonitis in 302 consecutive patients in Ibadan, Nigeria. Ann Ibd. Pg. Med [Internet]. 2016 [citado 26 Ene 2019];14(1):30-4. Disponible en: https://www.ajol.info/index.php/aipm/article/download/144280/133936/0

  18. Budzyński P, Dworak J, Natkaniec M, Pędziwiatr M, Major P, Migaczewski M, et al. The usefulness of the Mannheim Peritonitis Index score in peritonitis. Pol Przegl Chir [Internet]. 2015 [citado 26 Ene 2019];87(6):301-6. Disponible en: https://www.researchgate.net/profile/Maciej_Matlok/publication/280870262_The_usefulness_of_the_Mannheim_Peritonitis_Index_score_in_assessing_the_condition_of_patients_treated_for_peritonitis/links/55cbb2b408aebc967dfe1d6c/The-usefulness-of-the-Mannheim-Peritonitis-Index-score-in-assessing-the-condition-of-patients-treated-for-peritonitis.pdf

  19. Gascón-Ferrer I. Análisis de resultados y comportamiento de índices pronósticos en las peritonitis secundarias comunitarias de origen colónico [Internet]. Zaragoza: Universidad de Zaragoza; 2017 [citado 26 Ene 2019]. Disponible en: https://zaguan.unizar.es/record/56346/files/TESIS-2016-171.pdf

  20. Colsa-Gutiérrez P. Factores de riesgo de morbi-mortalidad tras cirugía abdominal urgente en pacientes mayores de 70 años. Estudio poblacional en Cantabria, Santander, diciembre de 2016. [Internet]. Cantabria: Universidad de Cantabria; 2017 [citado 26 Ene 2019]. Disponible en: https://www.tdx.cat/bitstream/handle/10803/402900/TesisPCG.pdf?sequence=1




2020     |     www.medigraphic.com