2021, Number 2
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salud publica mex 2021; 63 (2)
Markers of kidney function among SARS-CoV-2 infected patients. A rapid review of the literature.
Salazar-Martínez E, Hernández-Mariano JÁ, Galván-Portillo M, Baltazar-Reyes MC, Parra-Cabrera MS, Tamayo y Orozco JA, Cupul-Uicab LA
Language: Spanish
References: 61
Page: 253-261
PDF size: 377.19 Kb.
ABSTRACT
Objective. To summarize the scientific literature on kidney
abnormalities associated with SARS-CoV-2 infection.
Materials
and methods. It was conducted a rapid review using
the Cochrane methodology.
Results. Pre-existing chronic
kidney disease (CKD) in SARS-CoV-2 infected patients ranged
from 1-38% and acute kidney injury (AKI) ranged from 2.9-
86.4%. The prognosis of patients with SARS-CoV-2 infection
was worse among those with CKD and those with normal
remnant kidney function (RKF) that developed AKI. The risk
of death was higher (pooled risk ratio =1.49; 95%CI: 1.09-
2.04) among SARS-CoV-2 infected patients with pre-existing
CKD. The RKF markers showed alterations among severe
and non-surviving SARS-CoV-2 patients; the most common
marker was serum creatinine.
Conclusions. The scientific
evidence shows the relevance of the evaluation and permanent
monitoring of the RKF in SARS-CoV-2 hospitalized
patients to improve the prognosis of those with pre-existing
CKD as well as the prognosis of those without CKD who
develop AKI.
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