2021, Number 1
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Acta Med 2021; 19 (1)
Incidence of postcholecystectomy syndrome in adult patients
Aldama LKE, Alberti MP, Sanabria TR
Language: Spanish
References: 34
Page: 61-66
PDF size: 170.20 Kb.
ABSTRACT
Introduction: Laparoscopic cholecystectomy (CL) is the optimal treatment of cholelithiasis, but the persistence of symptoms is frequent and it's called postcholecystectomy syndrome (SPC). In this study, we aimed to determine the incidence of this syndrome.
Material and methods: An observational transversal study was performed, 220 clinical records from adult patients who had been done CL in 2017 at the
Hospital Nuevo Sanatorio Durango were analyzed. It has been evaluated the five most frequent gastrointestinal symptoms: right upper quadrant abdominal pain, nausea, vomiting, diarrhea and abdominal distension, before and a year after the surgery.
Results: SPC was present in 23.1% of cases (n = 36), the persistent symptoms were: abdominal distension (21.8%), pain (14.7%), nausea (5.8%), diarrhea (4.5%) and vomiting (0.6%). The number of patients reporting biliary pain, nausea and vomiting reduced significantly over a year of the surgery. The surgery didn't modify the risk of presenting diarrhea, but it is a risk factor to present abdominal distension (OR 2.08). 10 patients had no final diagnosis (32.3%).
Conclusion: SPC is frequent, patients should be carefully examined to exclude postoperative complications. CL has been associated with increased incidence of irritable bowel syndrome.
REFERENCES
División Técnica de Información Estadística en Salud. El IMSS en cifras. Las intervenciones quirúrgicas. Rev Med Inst Mex Seguro Soc. 2005; 43 (6): 511-520.
Enríquez-Sánchez LB, García-Salas JD, Carrillo-Gorena J. Colecistitis crónica y aguda, revisión y situación actual en nuestro entorno. Cir Gen. 2018; 40 (3): 175-178.
Duncan CB, Riall TS. Evidence-based current surgical practice: calculous gallbladder disease. J Gastrointest Surg. 2012; 16 (11): 2011-2025.
García RA, Gutiérrez RL, Cueto GJ. Evolución histórica de la cirugía laparoscópica. Rev Mex Cir Endoscop. 2016; 17 (2): 93-106.
Chousleb E, Chousleb A, Shuchleib S. Estado actual de la colecistectomía laparoscópica. Revista de gastroenterológica mexicana. Rev Gastroenterol Mex. 2004; 69 (Supl. 1): 28-35.
Memon MA, Deeik RK, Maffi TR, Fitzgibbons RJ Jr. The outcome of unretrieved gallstones in the peritoneal cavity during laparoscopic cholecystectomy. A prospective analysis. Surg Endosc. 1999; 13 (9): 848-857.
MacFadyen BV Jr, Vecchio R, Ricardo AE, Mathis CR. Bile duct injury after laparoscopic cholecystectomy. The United States experience. Surg Endosc. 1998; 12 (4): 315-321.
Vander Velpen GC, Shimi SM, Cuschieri A. Outcome after cholecystectomy for symptomatic gall stone disease and effect of surgical access: laparoscopic v open approach. Gut. 1993; 34 (10): 1448-1451.
Wanjura V, Sandblom G. How do quality-of-life and gastrointestinal symptoms differ between post-cholecystectomy patients and the background population? World J Surg. 2016; 40 (1): 81-88.
Jaunoo SS, Mohandas S, Almond LM. Postcholecystectomy syndrome (PCS). Int J Surg. 2010; 8 (1): 15-17.
O'Rourke NA, Jansen A. Post cholecystectomy symptoms. In: Cox M, Eslick G, Padbury R editors. The management of gallstone disease. New York, USA: Springer International Publishing; 2018. pp. 205-219.
Ros E, Zambon D. Postcholecystectomy symptoms. A prospective study of gall stone patients before and two years after surgery. Gut. 1987; 28 (11): 1500-1504.
Luman W, Adams WH, Nixon SN, Mcintyre IM, Hamer-Hodges D, Wilson G et al. Incidence of persistent symptoms after laparoscopic cholecystectomy: a prospective study. Gut. 1996; 39 (6): 863-866.
Yueh TP, Chen FY, Lin TE, Chuang MT. Diarrhea after laparoscopic cholecystectomy: associated factors and predictors. Asian J Surg. 2014; 37 (4): 171-177.
Schofer JM. Biliary causes of postcholecystectomy syndrome. J Emerg Med. 2010; 39 (4): 406-410.
Manríquez E, Tejos R, Rojas A, Pimentel E, Vega T, Achurra P et al. Diarrea poscolecistectomía: ¿un problema frecuente? Rev Chil Cir. 2017; 69 (5): 376-381.
Lamberts MP, Lugtenberg M, Rovers MM, Roukema AJ, Drenth JP, Westert GP et al. Persistent and de novo symptoms after cholecystectomy: a systematic review of cholecystectomy effectiveness. Surg Endosc. 2013; 27 (3): 709-718.
Arlow FL, Dekovich AA, Priest RJ, Beher WT. Bile acid-mediated postcholecystectomy diarrhea. Arch Intern Med. 1987; 147 (7): 1327-1329.
Schiller LR. Secretory diarrhea. Curr Gastroenterol Rep. 1999;1: 389-397.
Ruiz-Campos L, Gisbert JP, Ysamat M, Arau B, Loras C, Esteve M et al. Systematic review with meta-analysis: the prevalence of bile acid malabsorption and response to colestyramine in patients with chronic watery diarrhoea and previous cholecystectomy. Aliment Pharmacol Ther. 2019; 49 (3): 242-250.
Mertens MC, De Vries J, Scholtes VP, Jansen P, Roukema JA. Prospective 6 weeks follow-up post-cholecystectomy: the predictive value of pre-operative symptoms. J Gastrointest Surg. 2009; 13 (2): 304-311.
Berger MY, Olde Hartman TC, Bohnen AM. Abdominal symptoms: do they disappear after cholecystectomy? Surg Endosc. 2003; 17 (11): 1723-1728.
Bisgaard T, Rosenberg J, Kehlet H. From acute to chronic pain after laparoscopic cholecystectomy: a prospective follow-up analysis. Scand J Gastroenterol. 2005; 40 (11): 1358-1364.
Zhang J, Lu Q, Ren YF, Dong J, Mu YP, Lv Y et al. Factors relevant to persistent upper abdominal pain after cholecystectomy. HPB (Oxford). 2017; 19 (7): 629-637.
McNally MA, Locke GR, Zinsmeister AR, Schleck CD, Peterson J, Talley NJ. Biliary events and an increased risk of new onset irritable bowel syndrome: a population-based cohort study. Aliment Pharmacol Ther. 2008; 28 (3): 334-343.
Farahmandfar MR, Chabok M, Alade M, Bouhelal A, Patel B. Post cholecystectomy diarrhoea - a systematic review. Surg Sci. 2012; 3 (6): 332-338.
Amieva-Balmori M, Azamar-Jácome AA, Rojas-Carrera SI, Cano-Contreras AD, Remes-Troche JM. Prevalence of irritable bowel syndrome in cholecystectomized patients. Is there any association? Med Int Mex. 2016; 32 (2): 161-168.
Fall K, Ye W, Nyrén O. Risk for gastric cancer after cholecystectomy. Am J Gastroenterol. 2007; 102 (6): 1180-1184.
Aprea G, Canfora A, Ferronetti A, Giugliano A, Guida F, Braun A et al. Morpho-functional gastric pre-and post-operative changes in elderly patients undergoing laparoscopic cholecystectomy for gallstone related disease. BMC Surg. 2012; 12 Suppl 1: S5.
Mercan E, Duman U, Tihan D, Dilektasli E, Senol K. Cholecystectomy and duodenogastric reflux: interacting effects over the gastric mucosa. Springerplus. 2016; 5 (1): 1970.
Ozkaya M, Erten A, Sahin I, Engin B, Ciftçi A, Cakal E et al. The effect of ursodeoxycholic acid treatment on epidermal growth factor in patients with bile reflux gastritis. Turk J Gastroenterol. 2002; 13 (4): 198-202.
Zaniewski M, Ziaja K, Nowakowski P, Zabski M, Kuszewski M. Is a post-cholecystectomy syndrome the result of inappropriate preoperative diagnosis? Wiad Lek. 1999; 52 (11-12): 587-590.
Isherwood J, Oakland K, Khanna A. A systematic review of the aetiology and management of post cholecystectomy syndrome. Surgeon. 2019; 17 (1): 33-42.
Peterli R, Schuppisser JP, Herzog U, Ackermann C, Tondelli PE. Prevalence of postcholecystectomy symptoms: long-term outcome after open versus laparoscopic cholecystectomy. World J Surg. 2000; 24 (10): 1232-1235.