2020, Number 3
Characterization of diabetic patients infected with COVID-19 admitted to the OGR hospital. Torino, Italy
Language: Spanish
References: 12
Page:
PDF size: 135.20 Kb.
ABSTRACT
Introduction: The development of virulence of SARS CoV-2 has a very close relationship with diabetes mellitus.Objective: To characterize the diabetic patients infected with COVID-19, admitted to the OGR hospital.
Methods: A descriptive, cross-sectional study was carried out. The universe of study was the totality of patients admitted to the Hospital for COVID-19, OGR. The sample was 38 patients admitted with a diagnosis of diabetes mellitus.
Results: The predominant sex was male, with 55%, and the age group was from 71 to 80 years, with 36.8%. The most frequent comorbidities were high blood pressure with 100%, chronic kidney disease, with 73.7%, obesity, with 76.3%, ischemic heart disease, with 63.1%, chronic obstructive pulmonary disease, with 44, 7%, ICTUS with 21%, and neoplasms with 15.8%. Insulin was used in 63.1% of cases, metformin in 50%, and DPP-4 inhibitors in 34.2% of treated patients. Steroids were prescribed in 100% of cases. The presence of severe pneumonia was observed in 65.8% of patients, oxygen desaturation in 39.5%. 34.2% of the studied patients showed psychological stress, dietary transgressions occurred in 31.6% of the cases. Decompensated patients predominated, with 65.8% of cases on admission. 71% of patients improved the respiratory symptoms, as blood glucose levels were compensated.
Conclusions: Male patients between 71 and 80 years were the most affected. High blood pressure was the most frequent comorbidity. 71% of patients improved respiratory symptoms, as blood glucose levels were compensated.
REFERENCES
Hoffmann M, Kleine Weber H, Krüger N, Müller M, Drosten C, Pöhlmann S. The novel coronavirus 2019 (2019-nCoV) uses the SARS-coronavirus receptor ACE2 and the cellular protease TMPRSS2 for entry into target cells. Bio Rxiv. 2020[citado 24 /06/2020].Disponible en: https://www.biorxiv.org/content/10.1101/2020.01.31.929042v1
Rao S, Lau A, So HC. Exploring diseases/traits and blood proteins causally related to expression of ACE2, the putative receptor of SARS-CoV-2: A Mendelian Randomization analysis highlights tentative relevance of diabetes-related traits. Diabetes Care. 2020[citado 23/06/2020]; 43(7): 1416-1426.Disponible en: https://care.diabetesjournals.org/content/43/7/1416