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ISSN 1561-3186 (Electronic)

2019, Number 2

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Rev Acta Médica 2019; 20 (2)

Ocular perfusion pressure and intraocular pressure values in patients with systemic arterial hypertension

Zhao R, Márquez FM, del Pozo JH, Hidalgo T, Avila PY

Language: Spanish
References: 19
Page: 1-16
PDF size: 259.78 Kb.


ABSTRACT

Introduction: Hypertension is one of the global health problems that causes alterations of the target organs such as the kidney, brain, heart, retinal vessels and choroids in the eye. Ocular blood flow is determined by ocular perfusion pressure and vascular resistance.
Objective: To compare the intraocular pressure and ocular perfusion pressure values in patients with arterial hypertension with such values in healthy subjects.
Method: A descriptive, cross-sectional study was carried out with 57 patients diagnosed with essential systemic arterial hypertension and with a control group of 24 people of both sexes, aged 18-60 years.
Results: There is a significant difference in intraocular pressure values between the two groups of hypertensive cases and the healthy group. There is approximately 10 mmHg of difference in the median values of ocular perfusion pressure in uncontrolled cases in relation to the other two groups. There is a correlation between ocular perfusion pressure and mean arterial pressure, but not with intraocular pressure.
Conclusions: Blood pressure improves and influences ocular perfusion pressure values more than intraocular pressure. The ocular perfusion pressure values in compensated hypertensive patients behaved similar as in healthy cases.


REFERENCES

  1. Pérez Caballero MD, León Álvarez JL, Dueñas Herrera A, Alfonzo Guerra JP, Navarro Despaigne DA, Del Pozo Jerez HA, et al. Guía cubana de diagnóstico, evaluación y tratamiento de la hipertensión arterial. Rev Cubana Med. 2017 [acceso: 20/12/2018];56(4). Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S0034-752320170004 00001

  2. Oparil S, Acelajado MC, Bakris GL, Berlowitz DR, Cífková R, Dominiczak AF, et al. Hypertension, Nat Rev Dis Primers. 2018;4:18014. PubMed: PMID: 29565029.

  3. Cuba. Ministerio de Salud Pública. Morbilidad. En: Anuario estadístico de Salud 2017. La Habana: Dirección Nacional de Estadística; 2017. p. 97.

  4. Wang Z, Chen Z, Zhang L, Wang X, Hao G, Zhang Z, et al. Status of hypertension in China: results from the china hypertension survey 2012-2015. Circulation. 2018;137(22):2344-56. PubMed: PMID: 29449338.

  5. Sánchez Salorio M. Hipertensión arterial. En: Sánchez Salorio M, Díaz-Llopis M, Benitez del Castillo JM, Rodríguez Ares MT. Manifestaciones oftalmológicas de las enfermedades generales. España: Sociedad Española de Oftalmología; 2001.

  6. Caprioli J, Coleman A, Blood pressure, perfusion pressure, and glaucoma. Am J Ophthalmol. 2010;149:704-12.

  7. Luo X, Shen YM, Jiang MN, Lou XF, Shen Y. Ocular blood flow autoregulation mechanisms and methods. J Ophthalmol. 2015 [acceso: 20/12/2018](12):1-7. Disponible en: https://www.hindawi.com/journals/joph/2015/864871/abs/

  8. Guía de práctica clínica. Diagnóstico y tratamiento del glaucoma primario de ángulo abierto: evidencias y recomendaciones. 2016 [acceso: 20/12/2018]. Disponible en: http://www.cenetec-difusion.com/CMGPC/IMSS-164-09/ER.pdf

  9. Chung HJ, Hwang HB, Lee NY. The association between primary open-angle glaucoma and blood pressure: two aspects of hypertension and hypotension. Biomed Res Int. 2015;2015:827516. PubMed: PMID: 25557702.

  10. He Z, Nguyen CT, Armitage JA, Vingrys AJ, Bui BV. Blood pressure modifies retinal susceptibility to intraocular pressure elevation. PLoS One. 2012;7(2):e31104.

  11. Bowe A, Grünig M, Schubert J, Demir M, Hoffmann V, Kütting F, et al. Circadian variation in arterial blood pressure and glaucomatous optic neuropathy a systematic review and meta-analysis. Am J Hypertens. 2015(28):1077-81. PubMed: PMID: 25767134.

  12. Kanadani FN, Figueiredo CR, Miranda RM, Cunha PLT, Kanadani TCM, Dorairaj S. Ocular perfusion pressure and pulsatile ocular blood flow in normal and systemic hypertensive patients. J Curr Glaucoma Pract. 2015;9(1):16-9. PubMed: PMID: 26997827.

  13. Costa VP, Harris A, Anderson D, Stodtmeister R, Cremasco F. Ocular perfusion pressure in glaucoma. Acta Ophthalmol. 2014:92(4):252-66. PubMed: PMID: 24238296.

  14. Samsudin A, Isaacs N, Sharon Tai ML, Ramli N, Mimiwati Z, Choo MM. Ocular perfusion pressure and ophthalmic artery flow in patients with normal tension glaucoma. BMC Ophthalmol. 2016;16:36. PubMed: PMID: 27079202.

  15. Schmidla D, Garhofera G, Schmetterera L. The complex interaction between ocular perfusion pressure and ocular blood flow e relevance for glaucoma. Exp Eye Res. 2011;93(2):141-55.

  16. Hayreh SS, Podhajskya P, Zimmermanb MB. Role of nocturnal arterial hypotension in the development of ocular manifestations of systemic arterial hypertension. Curr Opin Ophthalmol. 1999;(10):474-82.

  17. Memarzadeh F, Ying Lai M, Chung J, Azen SP, Varma R. Blood pressure, perfusion pressure, and open-angle glaucoma: The Los Angeles Latino Eye Study. Invest Ophthalmol Vis Sci. 2010;51(6):2872-7.

  18. Van Koeverden AK, He Z, Nguyen CTO, Vingrys AJ, Bui BV. Systemic hypertension is not protective against chronic intraocular pressure elevation in a rodent model. Sci Rep. 2018;8(1):7107. PubMed: PMID: 29739991.

  19. Wang L, Cull GA, Fortune B. Optic nerve head blood flow response to reduced ocular perfusion pressure by alteration of either the blood pressure or intraocular pressure. Curr Eye Res. 2015;40(4):359-67. PubMed: PMID: 24911311.




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