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ISSN 1561-3186 (Electronic)

2019, Number 2

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Rev Acta Médica 2019; 20 (2)

Body mass index as a prognosis of survival in breast cancer patients in non-metastatic stages

Soriano GJL, Milanés RL, Batista AN, Lima PM, Ramón CI, Fleites CV

Language: Spanish
References: 32
Page: 1-19
PDF size: 397.20 Kb.


ABSTRACT

Introduction: Nutrition-related aspects are factors associated with prognosis for several cancers, including breast cancer.
Objective: To evaluate body mass index as a prognostic factor for the overall survival of patients operated on with a diagnosis of breast cancer.
Methods: A retrospective and observational study was carried out, which evaluated 1811 patients treated between 2006-2013 in the Clinical Oncology service of Hermanos Ameijeiras Clinical-Surgical Hospital. The main variable of the study was body mass index.
Results: The incidence was higher in patients 60 years of age and older (51.2%), postmenopausal women (72.4%), with white skin (52.6%), and overweight (40%). There was a predominance of patients with luminal B-HER2-negative immunophenotype (56.5%), negative nodes (55.8%), stages 2 or 3 (45.9% each) with a histological diagnosis of infiltrating ductal carcinoma (68%), and in early stages (74.3%). The body mass index was significantly related to the histological diagnosis and the clinical stage. In patients with a body mass index lower than 18.5 kg/m2 (underweight), the risk of death was 2.5 times higher compared to other groups. It could not be demonstrated that obesity was a prognostic factor that affected survival.
Conclusions: The results are not coincident with most of the articles published in the international medical literature on the subject. Future work with other more comprehensive anthropometric parameters is recommended.


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