2020, Number 4
<< Back Next >>
An Med Asoc Med Hosp ABC 2020; 65 (4)
Female fertility preservation techniques and our experience in the Centro Medico ABC Fertility Center
Álvarez VR, Monzón VM, Villagómez AMI, González CJ, Vázquez CEE, Navarro MC
Language: Spanish
References: 58
Page: 280-287
PDF size: 253.99 Kb.
ABSTRACT
Female fertility decreases gradually from the embryonic stage, increasing at the onset of menarche and declining again significantly after 37 years. The preservation of fertility consists of medical and / or surgical interventions designed to protect the fertility of patients in which their reproductive capacity is threatened by the natural aging of the ovaries or by different medical conditions that diminish or compromise the ovarian reserve. Thanks to biotechnological advances in the area of assisted reproduction, it is now possible to prevent the loss of fertility with excellent results (increase in the number of newborns) obtained from the cryopreservation of embryos, oocytes and / or ovarian tissue. Patients who are candidates for this kind of techniques must have a multidisciplinary medical care that allows them to individualize their approach so it’s of extreme importance that physicians are acquainted with the available treatment options to provide timely guidance. This article reviews the most important fertility preservation techniques, specific indications, effectiveness and safety, ending with an analysis of the experience gained over a period of 8 years in the Fertility Center of the ABC Medical Center.
REFERENCES
Gris Martínez JM, Callejo Olmos J, Pérez Milán F. Preservation of fertility in women undergoing cytotoxic therapies. Med Clin (Barc). 2011; 137 (15): 702-707.
Cabry R, Merviel P, Hazout A, Belloc S, Dalleac A, Copin H et al. Management of infertility in women over 40. Maturitas. 2014; 78 (1): 17-21. doi: 10.1016/j.maturitas.2014.02.014.
Garrido-Colino C, Lassaletta A, Vazquez MA, Echevarria A, Gutierrez I, Andión M et al. Current situation on fertility preservation in cancer patients in Spain: Level of knowledge, information, and professional involvement. An Pediatr (Barc). 2017; 87 (1): 3-8.
Woodard TL, Hoffman AS, Covarrubias LA, Holman D, Schover L, Bradford A et al. The Pathways fertility preservation decision aid website for women with cancer: development and field testing. J Cancer Surviv. 2018; 12 (1): 101-114.
Jones G, Hughes J, Mahmoodi N, Smith E, Skull J, Ledger W. What factors hinder the decision- making process for women with cancer and contemplating fertility preservation treatment? Hum Reprod Update. 2017; 23 (4): 433-457.
Algarroba GN, Sanfilippo JS, Valli-Pulaski H. Female fertility preservation in the pediatric and adolescent cancer patient population. Best Pract Res Clin Obstet Gynaecol. 2018; 48: 147-157.
Anderson RA, Wallace WHB, Telfer EE. Ovarian tissue cryopreservation for fertility preservation: clinical and research perspectives. Hum Reprod Open. 2017; 2017 (1): hox001. doi: 10.1093/hropen/hox001.
Lambertini M, Ceppi M, Poggio F, Peccatori FA, Azim HA Jr, Ugolini D et al. Ovarian suppression using luteinizing hormone-releasing hormone agonists during chemotherapy to preserve ovarian function and fertility of breast cancer patients: a meta-analysis of randomized studies. Ann Oncol. 2015; 26 (12): 2408-2419. doi: 10.1093/annonc/mdv374.
Zapardiel I, Diestro MD, Aletti G. Conservative treatment of early stage ovarian cancer: oncological and fertility outcomes. Eur J Surg Oncol. 2014; 40 (4): 387-393. doi: 10.1016/j.ejso.2013.11.028.
Moravek MB, Confino R, Smith KN, Kazer RR, Klock SC, Lawson AK et al. Long-term outcomes in cancer patients who did or did not pursue fertility preservation. Fertil Steril. 2018; 109 (2): 349-355.
De la Fuente L, Ortega S, Monzó A, Martín B, Iñarra MJ, Hernández C et al. Preservación de la fertilidad en endometriosis: estado actual de conocimiento y papel del sistema público de salud. Medicina Reproductiva y Embriología Clínica. 2016; 3 (3): 119-127.
Martinez F; International Society for Fertility Preservation–ESHRE–ASRM Expert Working Group. Update on fertility preservation from the Barcelona International Society for Fertility Preservation-ESHRE-ASRM 2015 expert meeting: indications, results and future perspectives. Fertil Steril. 2017; 108 (3): 407-415.e11.
Steta-Mondragón JR, Valero OPA, Deschamps-Díaz H, Álvarez-Valero R. Teratoma bilateral y preservación de la fertilidad. An Med Asoc Med Hosp ABC. 2012; 57 (4): 325-331.
Rodríguez GAN, Osorio SSB, Maldonado VMR, Faugier FE. Lupus eritematoso generalizado juvenil: patrones clínicos e inmunológicos en una cohorte de 150 pacientes del Hospital Infantil de México "Federico Gómez". An Med Asoc Med Hosp ABC. 2016; 61 (3): 182-187.
Lugones Botell M. Preserving fertility from primary health care. Rev Cuba Obstet Ginecol. 2014; 40 (3): 301-302.
Qiao J, Li R. Fertility preservation: challenges and opportunities. Lancet. 2014; 384 (9950): 1246-1247. doi: 10.1016/S0140-6736(14)61749-9.
Menjón BS. ¿Debemos incorporar la preservación de la fertilidad en el protocolo diagnóstico-terapéutico del cáncer? Rev Senol Patol Mamar. 2017; 30 (1): 1-2.
Garcia-Velasco JA, Domingo J, Cobo A, Martínez M, Carmona L, Pellicer A. Five years’ experience using oocyte vitrification to preserve fertility for medical and nonmedical indications. Fertil Steril. 2013; 99 (7): 1994-1999.
Soriano-Ortega KP, Carballo-Mondragón E, Roque-Sánchez AM, Durán-Monterrosas L, Kably-Ambe A. Percepción de la fertilidad en mujeres en edad reproductiva, según su edad. Ginecol Obstet Mex. 2017; 85 (6): 364-373.
Ramos RR, Gutiérrez GR, Monroy IA, Sánchez HG. Factores de riesgo asociados con infertilidad femenina. Ginecol Obstet Mex. 2008; 76 (12): 717-721.
Brugo-Olmedo S, Chillik C, Kopelman S. Definición y causas de la infertilidad. Rev Colomb Obstet Ginecol. 2003; 54 (4): 227-248.
De Munck N, Vajta G. Safety and efficiency of oocyte vitrification. Cryobiology. 2017; 78: 119-127. doi: 10.1016/j.cryobiol.2017.07.009.
Santo EVE, Dieamant F, Petersen CG, Mauri AL, Vagnini LD, Renzi A et al. Social oocyte cryopreservation: a portrayal of Brazilian women. JBRA Assist Reprod. 2017; 21 (2): 101-104.
Kutluk Oktay, MD, FACOG. Fertility preservation: we are in this a long haul. Editotial. Am J Obstet Gynecol. 2013: 77-79.
Pouly JL, Brugnon F, Pons H, Dejardin M, Tartiere M, Gremeau AS et al. Donación de gametos y de embriones. EMC -Ginecología - Obstetricia. 2014; 50 (1): 1-14.
Trounson A, Mohr L. Human pregnancy following cryopreservation, thawing and transfer of an eight-cell embryo. Nature. 1983; 305 (5936): 707-709.
Camus A. Preservación de la fertilidad en la mujer. Rev Med Clin Condes. 2010; 21 (3): 440-449.
Rodriguez-Wallberg KA, Oktay K. Options on fertility preservation in female cancer patients. Cancer Treat Rev. 2012; 38 (5): 354-361.
Almodin CG, Ceschin A, Nakano RE, Radaelli MR, Almodin PM, Silva CG et al. Vitrification of human oocytes and its contribution to in vitro fertilization programs. JBRA Assist Reprod. 2015; 19 (3): 135-140.
Massarotti C, Scaruffi P, Lambertini M, Remorgida V, Del Mastro L, Anserini P. State of the art on oocyte cryopreservation in female cancer patients: A critical review of the literature. Cancer Treat Rev. 2017; 57: 50-57.
De Vos M, Smitz J, Woodruff TK. Fertility preservation in women with cancer. Lancet. 2014; 384 (9950): 1302-1310. doi: 10.1016/S0140-6736(14)60834-5. Erratum in: Lancet. 2015; 385 (9971): 856.
Shi Q, Xie Y, Wang Y, Li S. Vitrification versus slow freezing for human ovarian tissue cryopreservation: a systematic review and meta-anlaysis. Sci Rep. 2017; 7 (1): 8538.
Practice Committees of the American Society for Reproductive Medicine and the Society for Assisted Reproductive Technology. Mature oocyte cryopreservation: a guideline. Fertil Steril. 2013; 99 (1): 37-43.
Gook DA, Choo B, Bourne H, Lewis K, Edgar DH. Closed vitrification of human oocytes and blastocysts: outcomes from a series of clinical cases. J Assist Reprod Genet. 2016; 33 (9): 1247-1252.
Cobo A, Serra V, Garrido N, Olmo I, Pellicer A, Remohí J. Obstetric and perinatal outcome of babies born from vitrified oocytes. Fertil Steril. 2014; 102 (4): 1006-1015.e4.
Crawford S, Boulet SL, Kawwass JF, Jamieson DJ, Kissin DM. Cryopreserved oocyte versus fresh oocyte assisted reproductive technology cycles, United States, 2013. Fertil Steril. 2017; 107 (1): 110-118.
Ho JR, Woo I, Louie K, Salem W, Jabara SI, Bendikson KA et al. A comparison of live birth rates and perinatal outcomes between cryopreserved oocytes and cryopreserved embryos. J Assist Reprod Genet. 2017; 34 (10): 1359-1366.
Edgar DH, Gook DA. A critical appraisal of cryopreservation (slow cooling versus vitrification) of human oocytes and embryos. Hum Reprod Update. 2012; 18 (5): 536-554.
Comtet M, Benard J, Grynberg M. Preservación de la fertilidad femenina. EMC Ginecol-Obst. 2017; 53 (1): 1-15.
Álvarez A. ¿Cuál sería la edad máxima para recomendar la preservación de la fertilidad por indicación no médica (indicación social)? En: Bruna I, Coroleu B. Lo esencial en Medicina Reproductiva. 2a edición. Barcelona: Elsevier; 2017. pp. 238-240.
Haino T, Tarumi W, Kawamura K, Harada T, Sugimoto K, Okamoto A et al. Determination of follicular localization in human ovarian cortex for vitrification. J Adolesc Young Adult Oncol. 2018; 7 (1): 46-53.
Bastings L, Beerendonk CC, Westphal JR, Massuger LF, Kaal SE, van Leeuwen FE et al. Autotransplantation of cryopreserved ovarian tissue in cancer survivors and the risk of reintroducing malignancy: a systematic review. Hum Reprod Update. 2013; 19 (5): 483-506.
Kristensen SG, Giorgione V, Humaidan P, Alsbjerg B, Bjørn AB, Ernst E et al. Fertility preservation and refreezing of transplanted ovarian tissue-a potential new way of managing patients with low risk of malignant cell recurrence. Fertil Steril. 2017; 107 (5): 1206-1213.
Jadoul P, Guilmain A, Squifflet J, Luyckx M, Votino R, Wyns C et al. Efficacy of ovarian tissue cryopreservation for fertility preservation: lessons learned from 545 cases. Hum Reprod. 2017; 32 (5): 1046-1054.
Andersen CY. Success and challenges in fertility preservation after ovarian tissue grafting. Lancet. 2015; 385 (9981): 1947-1948. doi: 10.1016/S0140-6736(15)60960-6.
Silber S. Ovarian tissue cryopreservation and transplantation: scientific implications. J Assist Reprod Genet. 2016; 33 (12): 1595-1603.
Di Pietro M, Virdis A, González FJ. Preservar la fertilidad en Pediatría a partir de la congelación de tejido ovárico: ¿Cuál es el mejor interés de la niña? Revista Pax et Emerita.2015; 11: 87-100.
Sánchez M, Edurne RE, Busso C, Pellice A. Inducción de la ovulación. Capítulo: Criopreservación y autotrasplante de tejido ovárico. España, S.L.: Elsevier; 2014.
Stachs A, Hartmann S, Gerber B. Preservation of fertility or ovarian function in patients with breast cancer or gynecologic and internal malignancies. Geburtshilfe Frauenheilkd. 2017; 77 (8): 861-869.
Álvarez A. ¿En qué casos está indicada la congelación de tejido ovárico en una preservación de la fertilidad?. En: Bruna I, Coroleu B. Lo esencial en medicina reproductiva. 2a edición. Barcelona: Elsevier; 2017. pp. 247-249.
Aguilar Melgar AE. Enfoque de la preservación de la fertilidad femenina. Rev Mex Reprod. 2013; 5: 157-158.
Lombardi EP, Sícaro LV. Preservación de la fertilidad. Rev Endocrinol Ginecol Reprod. 2003; 44-55.
López-Rioja MJ, Campos-Cañas JA, Recio-López Y, Quiroz-Garza G, Sánchez-González CM, Hinojosa-Rodríguez K et al. Optimal number of oocytes: in vitro fertilization predictive model. Ginecol Obstet Mex. 2017; 85 (11): 735-747.
Medrano JV, Andrés MDM, García S, Herraiz S, Vilanova-Pérez T, Goossens E et al. Basic and clinical approaches for fertility preservation and restoration in cancer patients. Trends Biotechnol. 2018; 36 (2): 199-215. doi: 10.1016/j.tibtech.2017.10.010.
Urech C, Ehrbar V, Boivin J, Müller M, Alder J, Zanetti Dällenbach R et al. Knowledge about and attitude towards fertility preservation in young female cancer patients: a cross-sectional online survey. Hum Fertil (Camb). 2018; 21 (1): 45-51.
Gunnala V, Schattman G. Oocyte vitrification for elective fertility preservation: the past, present, and future. Curr Opin Obstet Gynecol. 2017; 29 (1): 59-63.
Lineamientos de infertilidad. Ginecol Obstet Mex. 2011; 79 (11): 659-673.
Schwarze JE, Zegers F, Galdames V. Reproducción asistida en Latinoamérica y Chile Rev Med Clin Condes. 2010; 21 (3): 451-456.
EVIDENCE LEVEL
III