2020, Number 1
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Rev Cub Oftal 2020; 33 (1)
Refractive modifications after treatment of keratoconus with corneal crosslinking in eight years of evolution
Jareño OM, Pérez PZ, Castillo PA, Padilla GC, León RY, de los Santos AKV
Language: Spanish
References: 19
Page: 1-9
PDF size: 330.03 Kb.
ABSTRACT
Objectives: Determine the refractive modifications in patients with keratoconus treated with
corneal crosslinking in eight years of evolution.
Methods: A descriptive, longitudinal and retrospective study was performed in 58 eyes of 58
patients with progressive keratoconus, operated with corneal crosslinking in 2009. Statistical
analysis was performed with the T-test for paired data, with 95% significance.
Results: Female sex predominated with 55.2%. The mean age was 27.6 ± 6.7 years and stage
II according to Amsler-Krumeich, with 53.4%. The final mean of uncorrected visual acuity,
best corrected, sphere, cylinder, and spherical equivalent was 0.34 ± 0.25; 0.63 ± 0.19; 6.16 ±
3.32 diopters; -2.81 ± 2.00 dioptres and -7.41 ± 3.69 dioptres respectively.
Conclusions: In the treatment of progressive keratoconus with corneal crosslinking, there is a significant improvement in uncorrected visual acuity and better corrected visual acuity, as well
as reduction of the sphere, cylinder and spherical equivalent.
REFERENCES
Gomes JAP, Tan D, Rapuano CJ, Belin MW, Ambrosio R, Güell JL, et al. Consenso global en queratocono y enfermedades ectásicas. Cornea. 2015;34:359-69.
Mora Valencia M, Bonilla Estévez C, Vargas Garzón O, Giraldo Valencia OL. Queratocono: una revisión y posible situación epidemiológica en Colombia. Cienc Bioméd. 2007;5(8):101- 212.
Wollensak G, Spoerl E, Seiler T. Riboflavin/ultraviolet-a-induced collagen Crosslinking for the treatment of keratoconus. Am J Ophthalmol. 2003;135(5):620-7.
Jareño Ochoa M, Escalona Leyva E, López Hernández S, Castillo Pérez A, Pérez Parra Z, Márquez Villalón S. Comportamiento de los trasplantes de córnea. Rev Cubana Oftalmol. 2009;22:47-51.
Nicula C, Pop R, Rednik A, Nicula D. 10-Year Results of Standard Cross-Linking in Patients with Progressive Keratoconus in Romania. Journal of Ophthalmology. 2019,
Theuring A, Spoerl E, Pillunat LE, Raiskup F. Corneal collagen cross-linking with riboflavin and ultraviolet-A light in progressive keratoconus. Results after 10-year follow-up. Ophthalmol. 2015;112(2):140-7.
Khan WA, Zaheer N, Khan S. Corneal collagen cross-linking for keratoconus: Results of 3- year follow-up in Pakistani population. Can J Ophthalmol. 2015;50(2):143-50.
Raiskup F, Theuring A, Pillunat LE. Corneal collagen Crosslinking with riboflavin and ultraviolet-A light in progressive keratoconus: ten year results. J Cataract Refract Surg. 2015;41: 41–6.
Galvis ET. Corneal Cross-Linking in Keratoconus with five years of follow-up. Ophthalmol Eye Dis. 2016;8:17–21.
Seyedian MA, Aliakbari S, Miraftab M, Hashemi H, Asgari S, Khabazkhoob M. Corneal collagen cross-linking in the treatment of progressive keratoconus: a randomized controlled contralateral eye study. Mid East Afr J Ophthalmol. 2015;22(3):340-5.
Wittig-Silva C, Chan E, Islam FM. A randomized, controlled trial of corneal collagen cross-linking in progressive keratoconus: three-year results. Ophthalmology. 2014;121:812-21.
O'Brart DP, Patel P, Lascaratos G, Wagh VK, Tam C, Lee J, O'Brart NA. Corneal Crosslinking to Halt the Progression of Keratoconus and Corneal Ectasia: Seven-Year Follow-up. Am J Ophthalmol. 2015;160(6):1154-63.
Craig JA, Mahon J, Yellowlees A, Barata T, Glanville J, Arber M, Mandava L, Powell J, Figueiredo F. Epithelium-off photochemical corneal collagen cross-linkage using riboflavin and ultraviolet a for keratoconus and keratectasia: a systematic review and meta-analysis. Ocul Surf. 2014;12(3):202-14.
Maier P, Reinhard T, Kohlhaas M. Corneal collagen cross-linking in the stabilization of keratoconus. Dtsch Arztebl Int. 2019;116:184-90.
Caporossi A, Baiocchi S, Mazzotta C. Parasurgical therapy for keratoconus by riboflavinultraviolet type A rays induced cross-linking of corneal collagen: preliminary refractive results in an Italian study. J Cataract Refract Surg. 2006;32:837-45.
Goldich Y. Clinical and corneal biomechanical changes after collagen Crosslinking with riboflavin and UV irradiation in patients with progressive keratoconus: results after 2 years of follow-up. Cornea. 2012; 31:609–14.
Chunyu T, Xiujun P, Zhengjun F, Xia Z, Feihu Z. Corneal collagen cross-linking in keratoconus: a systematic review and meta-analysis. Sci Rep. 2014;4:5652.
Nicula C, Nicula D, Pop RN. Results at 7 years after cross-linking procedure in keratoconic patients. J Franç Ophtalmol. 2017;40(7):535-41.
Hashemi H, Seyedian MA, Miraftab M, Fotouhi A, Asgari S. Corneal collagen crosslinking with riboflavin and ultraviolet a irradiation for keratoconus: long-term results. Ophthalmology. 2013;120(8):1515-20.