2019, Number 4
Validation of neutrophil/lymphocyte index predictive of severity in the surgical cancer patient
Language: Spanish
References: 10
Page: 1-10
PDF size: 339.76 Kb.
ABSTRACT
Introduction: Inflammation plays a leading role in the pathophysiology of cancer. Objective: To validate the predictive severity neutrophil/lymphocyte index in the elective surgical oncology patient.Methods: A quasi-experimental study was carried out for a single group in surgical patients diagnosed with oncological disease, electively operated by the different surgical specialties at Marie Curie Cancer Hospital from January to December 2019.
Results: The Receiver Operating Characteristic curve was associated with the logistic regression model as it estimates the threshold of 0.23 above which the probability of severity will be declared. In the validation among the patients, there are 23 who did have a serious risk. These are the false positives on which the preoperative period was optimized.
Conclusions: The neutrophil/lymphocyte index showed utility in predicting severity in the surgical oncology patient, and made it possible to individualize the pre-surgical treatment so that it would be more successful.
REFERENCES
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Sarraf KM, Belcher E, Raevsky E, Nicholson AG, Goldstraw P, Lim E. Neutrophil/lymphocyte ratio and its association with survival after complete resection in non-small cell lung cancer. J Thorac Cardiovasc Surg. 2009[acceso: 23/10/2019];137;(2):425-8. Disponible en: https://www.clinicalkey.es/#!/content/playContent/1-s2.0- F
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Halazun KJ, Aldoori A, Malik HZ, Al-Mukhtar A, Prasaid KR, Toogood GJ, et al. Elevated preoperative neutrophil to lymphocyte ratio predicts survival following hepatic resection for colorectal liver metastases. Eur J Surg Oncol. 2008[acceso: 23/10/2019];34:55-60. Disponible en: https://www.clinicalkey.es/#!/content/playContent/1-s2.0-S0748798307000789?returnurl=https:%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS0748798307000789%3Fshowall%3Dtrue&referrer=https:%2F%2Fwww.ncbi.nlm.nih.gov%2F