2020, Number 4
<< Back Next >>
Acta Med 2020; 18 (4)
Parenteral paraquat poisoning
Fuentes MDA, del Real RR, Peña EM, Canizales RJA, Juárez SCA
Language: Spanish
References: 13
Page: 411-413
PDF size: 120.00 Kb.
ABSTRACT
Herbicides are agricultural products widely distributed worldwide. Paraquat (1,1’-dimethyl-4,4’-bipyridyl) is a potent bipyridyl-type herbicide and desiccant, which is available as a 20% standard solution. In Mexico, it is still highly used despite attempts to restrict it. Due to its high lethality, it is used for suicide purposes. The main route of administration is the gastrointestinal route, although some cases have been reported intravenously, intramuscularly and intradermally. Parenteral paraquat poisoning is extremely rare and is associated in most cases with suicide attempt. We present the case of a 13-year-old female, who self-administered paraquat intramuscularly and who developed lethal complications as a consequence of intoxication by said product, whose death occurred 20 days after administration of paraquat.
REFERENCES
Bejarano-González F. Los plaguicidas altamente peligrosos: nuevo tema normativo internacional y su perfil nacional en México. En: Bejarano-González F. Los plaguicidas altamente peligrosos en México. Primera edición. México: Red de Acción sobre Plaguicidas y Alternativas en México, A. C. 2017; pp. 13-138.
Raghu K, Mahesh V, Sasidhar P, Reddy PR, Venkataramaniah V, Agrawal A. Paraquat poisoning: a case report and review of literature. J Fam Community Med. 2013; 20: 198-200.
Viales-López G. Intoxicación por paraquat. Medicina Leg Costa Rica. 2014; 31 (2): 88-94.
Marín-Cuartas M, Berrouet-Mejía MC. Intoxicación por paraquat. Rev CES Med. 2016; 30 (1): 114-121.
Hernández J, Contreras-Zúñiga E, Zuluaga-Martínez S. Intoxicación por paraquat: descripción de un caso clínico. Acta Toxicol Argent. 2008; 16 (1): 5-8.
Harley JB, Grinspan S, Root RK. Paraquat suicide in a young woman: results of therapy directed against the superoxide radical. Yale J Biol Med. 1977; 50 (5): 481-488.
Lim SW, Lee WY, Han HS, Hahn JS, Kim MO, Kwon SK et al. A case of paraquat intoxication caused by intramuscular injection. Korean J Nephrol. 2004; 23: 505-508.
Gheshlaghi F, Eizadi-Mood N, Mohammad SA, Mahdy MS. Intramuscular injection of paraquat for suicidal attempt: a rare case report. Clin Toxicol. 2012; 50 (4): 270.
Caridad A, López Menchero R, Maduell F, Sigüenza F. Intoxicación con paraquat por vía parenteral. Nefrología. 1994; 14 (6): 707-710.
Ramirez SM, Bastidas O, Mujica Y, Pacheco FJ, Gómez PN, Abello MI. Intoxicación pediátrica por paraquat (Gramoxone). Supervivencia en dos casos. Archivos Venezolanos de Puericultura y Pediatría. 2010; 73 (1): 20-26.
Cartagena S, Díaz I, Gutiérrez C et al. Fibrosis pulmonar aguda asociada a intoxicación por paraquat: caso clínico. Rev Med Chile. 2018; 146: 938-941.
Nogué S, Munné P, Campañá E, Bertrán A, Reig R, Rodamilans M. Failure of a cyclophosphamide-dexamethasone combination in paraquat. Medicina Clínica. 1989; 2: 61-63.
Moreno-Rivillo M, Salinas-Aguilera R, Troncoso-Acuña J. Intoxicación severa por paraquat: a propósito de un caso. Revista Chilena de Medicina Intensiva. 2016; 31 (1): 27-30.