2020, Number 2
Therapeutic plateletapheresis for the management of essential thrombocitosis, case report and review of the method
Language: Spanish
References: 10
Page: 81-84
PDF size: 203.04 Kb.
ABSTRACT
Introduction: A case of an 82-year-old male is reported, who comes to our center presenting an essential thrombocytosis, with platelet levels › 2,000 x 103/µL. The patient was treated by therapeutic plateletapheresis performed with a donation kit. At the end of the last procedure, he presented improvement. Objective: The parameters used in apheresis equipment are described. Material and methods: An Amicus® apheresis machine, a platelet donation kit, was used. Results: It was necessary to modify the parameters of the apheresis machine to enable it and thus achieve the procedure, since it was not designed to perform therapeutic plateletapheresis procedures, because it does not allow the introduction of pathological parameters. Two series of 6 procedures were performed, one every 24 hours. At the end of each series there was a decrease in platelet count and decrease in its symptomatology. Conclusions: After the series of procedures, clinical improvement (decrease in associated symptoms) and laboratory (a return in platelet numbers to normal ranges) were presented. This treatment should be considered as a good alternative in sites that do not have specific equipment for the performance of therapeutic plateletapheresis.REFERENCES
Schwartz J, Padmanabhan A, Aqui N, Balogun RA, Connelly-Smith L, Delaney M et al. Guidelines on the use of therapeutic apheresis in clinical practice-evidence-based approach from the writing committee of the American Society for Apheresis: the seventh special issue: therapeutic apheresis-guidelines 2016. J Clin Apheresis. 2016; 31 (3): 149-338.
Schwartz J, Padmanabhan A, Aqui N, Balogun RA, Connelly-Smith L, Delaney M et al. Guidelines on the Use of Therapeutic Apheresis in Clinical Practice-Evidence-Based Approach from the Writing Committee of the American Society for Apheresis: The Seventh Special Issue. J Clin Apher. 2016; 31 (3): 149-162.