2020, Number 3
<< Back Next >>
Acta Med 2020; 18 (3)
Kidney transplant experience in private practice at Hospital Ángeles del Carmen
García OGA, Aceves QCA, Corona MJC
Language: Portugués
References: 15
Page: 274-283
PDF size: 220.82 Kb.
ABSTRACT
Introduction: There is little information on transplantation in private medical practice, particularly in developing countries. We documented the renal transplant experience at CENREN and Hospital Ángeles del Carmen.
Material and methods: A retrospective cohort study was conducted, obtaining demographic variables, time with nephropathy, renal replacement therapy (RRT), chemical analysis, renal function and survival.
Results: 58 patients were transplanted between 2005-2018. 43.4% were from a living related donor (LRD), 13.2% living unrelated donor (LUD) and 43.4% cadaveric donor (CD). The 5-year survival was 88% in recipients from CD, 94% LRD, and 100% LUD. Chronic rejection occurred in 13.8% (26.1% CD, 14.3% LUD and 4.3% LRD, p ‹ 0.05). 20% of cadaveric donor recipients required post-transplant RRT, 16.7% from living unrelated donor and none from the living related did, considering this as a risk factor for rejection (RR 37.0, 95% CI 5.35-255.7, p ‹ 0.05). 93.8% of living related donor maintains a KDIGO G1-3 (83.3 and 84.6% in recipients of living unrelated and cadaveric, respectively).
Conclusion: Results in kidney transplant in private medical practice in Mexico are similar to those reported by developed countries, some even better such as time of cold ischemia in cadaveric donor transplantation, use of basiliximab and renal function at five years.
REFERENCES
Hatzinger M, Stastny M, Grützmacher P, Sohn M. The history of renal transplantation. Urologue A. 2016; 55 (10): 1353-1359.
Barker CF, Markmann JF. Historical overview of transplantation. Cold Spring Harb Perspect Med. 2013; 3: a014977.
Murray JE, Merrill JP, Harrison JH, Wilson RE, Dammin GJ. Prononged survival of human-kidney homografts by immunosuppressive drug therapy. N Eng J Med. 1963; 268: 1315-1323.
Cecka JM. Kidney transplantation in the United States. Clin Transp. 2008: 1-18.
Monteón F, Gómez B, Valdespino C, Chávez S, Sandoval M, Flores A et al. The kidney transplant experience at Hospital de Especialidades, Centro Médico Nacional de Occidente, IMSS, Guadalajara, México. Clin Transpl. 2003; 165-174.
Baptista-González HA. Trasplante renal, a propósito de los primeros casos. Rev Invest Med Sur Mex. 2011; 18 (1): 32-34.
Hugues U. Kidney transplant in Nigeria: a single centre experience. 2016. Pan Afr Med J. 2016; 25.
Hasan S, Naqvi A, Hussain Z, Hashmi A, Akhtar F, Hussain M et al. Renal transplantation in developing countries. Kidney Int Suppl. 2003; 63 (83): S96-100.
Morales-Buenrostro LE, Marino-Vázquez LA, Alberú J. Four decades of the kidney transplantation program at the Institute Nacional de Ciencias Médicas y Nutrición Salvador Subirán in Mexico City. Clin Transp. 2009; 153-164.
Contreras C, García A, Hernández C, Portela J. Experiencia perioperatoria en el trasplante renal en un Hospital Privado en México. Acta Médica Grupo Ángeles. 2019; 17 (2): 126-130.
Guimarães J, Araújo A, Santos F, Nunes C, Casal M. Living-donor and deceased-donor renal transplantation: differences in early outcome-a single-center experience. Transplant Proc. 2015; 47: 958-962.
Matas A, Payne W, Sutherland D, Humar A, Gruessner R, Kandaswamy R et al. 2,500 living donor kidney transplants: a single-center experience. Ann Surg. 2001; 234 (2): 149-164.
Ojo A, Morales J, González-Molina M, Steffick D, Luan F, Merion R et al. Comparison of the long-term outcomes of kidney transplantation: USA versus Spain. Nephrol Dial Transplant. 2013; 28: 213-220.
Matter Y, Nagid A, Lotfy O, Alsayed A, Donia A, Redaie A. Impact of donor source on the outcome of live donor kidney transplantation: a single center experience. Nephrourol Mon. 2016; 8 (3): 1-8.
Hardinger K, Brennan D, Klein C. Selection of induction therapy in kidney transplantation. Transpl Int. 2012; 26: 662-672.