2020, Number 5
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salud publica mex 2020; 62 (5)
Age patterns of human papillomavirus infection as primary screening test for cervical cancer and subsequent triage with visual inspection in Honduras
Sandoval M, Holme F, Lobo S, Slavkovsky R, Thomson KA, Jeronimo J, Figueroa J, de Sanjose S
Language: English
References: 21
Page: 487-493
PDF size: 315.30 Kb.
ABSTRACT
Objective. To evaluate age patterns in human papillomavirus
(HPV) prevalence and visual inspection with acetic acid
(VIA) positivity among women participating in cervical cancer
screening in Honduras.
Materials and methods. Data on
the HPV status (careHPV) and subsequent VIA in HPV-positive
women were retrieved from three provinces within the Public
Health Sector.
Results. Between 2015 and 2018, 60 883
women aged 15-85 years were screened. HPV was detected
in 15%, with variation by age, peaking at 20-24 years (27.8%)
decreasing to 16% at 30-49 years. Differences in point age–
specific HPV prevalence were observed between provinces,
but with similar age pattern. VIA was positive in 24.5% of the
women aged 30-44 years.
Conclusions. The age pattern
of the HPV prevalence supports starting HPV testing at age
30+. The low positivity of VIA in ages close to menopause
suggest underdetection of cervical lesions in this age group.
REFERENCES
Ronco G, Dillner J, Elfström KM, Tunesi S, Snijders PJF, Arbyn M, et al. Efficacy of HPV-based screening for prevention of invasive cervical cancer: follow-up of four European randomised controlled trials. Lancet. 2014;383(9916):524-32. https://doi.org/10.1016/S0140-6736(13)62218-7
Bruni L, Diaz M, Castellsagué X, Ferrer E, Bosch FX, de Sanjosé S. Cervical human papillomavirus prevalence in 5 continents: metaanalysis of 1 million women with normal cytological findings. J Infect Dis. 2010;202(12):1789-99. https://doi.org/10.1086/657321
Franceschi S, Herrero R, Clifford GM, Snijders PJF, Arslan A, Anh PTH, et al. Variations in the age-specific curves of human papillomavirus prevalence in women worldwide. Int J Cancer. 2006;119(11):2677-84. https://doi. org/10.1002/ijc.22241
Schiffman M, Doorbar J, Wentzensen N, de Sanjosé S, Fakhry C, Monk BJ, et al. Carcinogenic human papillomavirus infection. Nat Rev Dis Primer. 2016;2:16086. https://doi.org/10.1038/nrdp.2016.86
World Health Organization. WHO Guidelines for Screening and Treatment of Precancerous Lesions for Cervical Cancer Prevention [Internet]. Geneva: WHO, 2013 [cited Aug 13, 2019]. Available from: http://www.ncbi. nlm.nih.gov/books/NBK195239/
Bray F, Ferlay J, Soerjomataram I, Siegel RL, Torre LA, Jemal A. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2018;68(6):394-424. https://doi.org/10.3322/caac.21492
Hall MT, Smith MA, Lew J-B, O’Hallahan J, Fentiman G, Neal H, et al. The combined impact of implementing HPV immunisation and primary HPV screening in New Zealand: Transitional and long-term benefits, costs and resource utilisation implications. Gynecol Oncol. 2019;152(3):472-9. https://doi.org/10.1016/j.ygyno.2018.10.045
de Sanjose S, Brotons M, LaMontagne DS, Bruni L. Human papillomavirus vaccine disease impact beyond expectations. Curr Opin Virol. 2019;39:16-22. https://doi.org/10.1016/j.coviro.2019.06.006
Brotherton JML. The remarkable impact of bivalent HPV vaccine in Scotland. BMJ. 2019;365: l1375. https://doi.org/10.1136/bmj.l1375
Maza M, Alfaro K, Garai J, Velado MM, Gage JC, Castle PE, et al. Cervical cancer prevention in El Salvador (CAPE)-An HPV testing-based demonstration project: Changing the secondary prevention paradigm in a lower middle-income country. Gynecol Oncol Rep. 2017;20:58-61. https://doi. org/10.1016/j.gore.2017.02.011
Toliman PJ, Kaldor JM, Badman SG, Gabuzzi J, Silim S, Kumbia A, et al. Performance of clinical screening algorithms comprising point-of-care HPV-DNA testing using self-collected vaginal specimens, and visual inspection of the cervix with acetic acid, for the detection of underlying high-grade squamous intraepithelial lesions in Papua New Guinea. Papillomavirus Res. 2018;6:70-6. https://doi.org/10.1016/j.pvr.2018.10.009
Hu L, Bell D, Antani S, Xue Z, Yu K, Horning MP, et al. An observational study of deep learning and automated evaluation of cervical images for cancer screening. J Natl Cancer Inst. 2019;111(9):923-32. https://doi. org/10.1093/jnci/djy225
Holme F, Jeronimo J, Maldonado F, Camel C, Sandoval M, Martinez- Granera B, et al. Introduction of HPV testing for cervical cancer screening in Central America: the Scale-Up project. Prev Med. 2020;135:106076. https://doi.org/10.1016/j.ypmed.2020.106076
Herrero R, González P, Markowitz LE. Present status of human papillomavirus vaccine development and implementation. Lancet Oncol. 2015;16(5):e206-16. https://doi.org/10.1016/S1470-2045(14)70481-4
Pinto D da S, Fuzii HT, Quaresma JAS. Prevalência de infecção genital pelo HPV em populações urbana e rural da Amazônia Oriental Brasileira. Cad Saúde Pública. 2011;27(4):769-78. https://doi.org/10.1590/S0102- 311X2011000400016
de Lima Soares V, de Mesquita AMTS, Cavalcante FGT, Silva ZP, Hora V, Diedrich T, et al. Sexually transmitted infections in a female population in rural north-east Brazil: prevalence, morbidity and risk factors. Trop Med Int Health TM IH. 2003;8(7):595-603. https://doi.org/10.1046/j.1365- 3156.2003.01078.x
Kasamatsu E, Rodríguez-Riveros MI, Soilan AM, Ortega M, Mongelós P, Páez M, et al. Factors associated with high-risk human papillomavirus infection and high-grade cervical neoplasia: A population-based study in Paraguay. PloS One. 2019;14(6):e0218016. https://doi.org/10.1371/journal. pone.0218016
Raifu AO, El-Zein M, Sangwa-Lugoma G, Ramanakumar A, Walter SD, Franco EL, et al. Determinants of Cervical Cancer Screening Accuracy for Visual Inspection with Acetic Acid (VIA) and Lugol’s Iodine (VILI) Performed by Nurse and Physician. PloS One. 2017;12(1):e0170631. https:// doi.org/10.1371/journal.pone.0170631
Castle P, Qiao Y-L, Zhao FH, Chen W, Valdez M, Zhang X, et al. Clinical determinants of a positive visual inspection after treatment with acetic acid for cervical cancer screening. BJOG. 2014;121(6):739-46. https://doi. org/10.1111/1471-0528.12646
Mustafa RA, Santesso N, Khatib R, Mustafa AA, Wiercioch W, Kehar R, et al. Systematic reviews and meta-analyses of the accuracy of HPV tests, visual inspection with acetic acid, cytology, and colposcopy. Int J Gynecol Obstet. 2016;132(3):259-65. https://doi.org/10.1016/j.ijgo.2015.07.024
Sandoval M, Slavkovsky R, Bansil P, Lim J, Figueroa J, de Sanjose S. Acceptability and safety of thermal ablation for the treatment of precancerous cervical lesions in Honduras. Trop Med Int Health. 2019;24(12):1391-99. https://doi.org/10.1111/tmi.13315