González RA, Palma MS, Molina CR, Borrero RY, Castro CYF, Pinillos ST, Velásquez VB

Language: Spanish
References: 22
Page: 85-89
PDF size: 100.46 Kb.

ABSTRACT

The viral ribonucleic acid (RNA) level in plasma or serum of type 1 human immunodeficiency virus (HIV-1) infected patients has become an important disease progression marker. A descriptive study of the microorganisms frequency infected 200 Cuban HIV-1 patients with high viral loads was achieved. The viral loads were determined by Nuclisens system and the CD4 + T lymphocytes count by flow cytometry. The HIV-1 viral loads ranged from 61,000 to 830,000 cp/mL and the median was 150,000 cp/mL. The microbiological studies showed that Streptococcus group D (13%), followed by Streptococcus group A (5%), Pseudomonas aeruginosa and Staphylococcus aureus (3%) were the predominant isolates in respiratory samples. The 8% of the analyzed sputa were positive to Acid Fast Bacilli. A 13% of cerebrospinal fluid samples were positive to the presence of Cryptococcus. Giardia lambia and Isospora belli (3% each) were the most frequent parasites found, followed by Fasciola hepatica, Entoameba histolitica, Entoameba coli and Criptosporidium parvum (1% each). The highest positivity of the analyzed samples was associated to a CD4 + T lymphocytes percentage lower than 240 cell/µL. No pathogenic microorganisms were isolated from patients with CD4 + T lymphocytes counts between 560-746 cell/mL.

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