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Federación Mexicana de Ginecología y Obstetricia, A.C.

2020, Number 08

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Ginecol Obstet Mex 2020; 88 (08)

Plasmacytoma of uterine cervix. A case report and literature review

Melero-Cortés LM, Morales-Zarco S, Vieites Pérez-Quintela MB, Martínez-Maestre MÁ

Language: Spanish
References: 21
Page: 554-561
PDF size: 387.50 Kb.


ABSTRACT

Background: The incidence of extramedullary plasmacytoma is low and, specifically, the gynecological location is exceptional. To date, 27 cases of gynecological plasmacytomas have been published (11 corresponding to cervical location).
Clinical case: 37-year-old patient, with no relevant medical history, who came to a consultation for abnormal uterine bleeding and bleeding. By spectroscopy, the hypertrophic and friable cervix was appreciated. Cervical biopsy verifies the diagnosis of plasmacytoma. Subsequently, an extension study ruled out involvement in other locations. Treatment consists of hysterectomy and pelvic lymphadenectomy, without adjuvant chemotherapy. The pathological and immunohistochemical studies confirmed the diagnosis. Currently, the patient is in follow-up and free of disease.
Conclusions: Due to the scarcity of published cases of cervical plasmacytoma, there is no reference treatment. Despite this, there do not appear to be any differences between the patients treated with radiotherapy or surgery. The rate of progression to multiple myeloma varies from 14-36%. The adjuvant therapy does not change the rate of progression to multiple myeloma, so it is contraindicated.


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