2020, Number 3
Med Crit 2020; 34 (3)
COVID-19 Physiopathology
Elizalde GJJ
Language: English
References: 0
Page: 173-175
PDF size: 112.44 Kb.
Text Extraction
In any clinical situtation physiopathology is of paramount importance in critical care. The disease caused by the new virus SARS-CoV-2, imposes important challenges and requires an understanding of the pathophysiological mechanisms involved in it as a means to design better management and life support protocols. This process is currently under construction, but progress has been made, which is summarized below.The final path of severe COVID-19 pneumonia is like that of many other serious medical conditions: ARDS, whose classical pathophysiological hallmarks are neutrophil-mediated inflammation, excessive transmigration and activation of leukocytes and platelets, incresed activation of coagulation pathways and enhanced permeability through the thin alveolar-capillary membrane,