Solís GV, Gómez CJF

Language: Spanish
References: 29
Page: 176-180
PDF size: 207.25 Kb.

ABSTRACT

Sex hormones play an important roll in orthodontic tooth movement. Therefore, the purpose of this study was to determinate the effect of estrogen and progestine combination in osteoclasts formation which was induced by mechanical stress. Material and methods: Thirty Wistar rats were used. The experimental group A received a combination of estrogen and progestine doses and the force produced by nickel-titanium wire appliance placed between upper first and second molar. The group B was injected with hormones such as group A but without nickel-titanium wire appliance. The group C was a control group just received the wire appliance force without hormones. Results: The group A demonstrated significant decrease in the number of osteoclasts (mean 16.60± 3.9 p ‹ 0.005) compared with group C (mean 21.30 ± 1.94 p ‹ 0.005). The group B demonstrated significant decrease in the number of osteoclasts compared with groups A and C (mean 0.8380 ± .4824 p ‹ 0.005). Conclusion: The findings suggets that this combination of estrogen and progestine caused an important decrease in the initial osteoclasts formation suppressing the effect in bone resorption.

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