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Medicina & Laboratorio

2013, Number 07-08

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Medicina & Laboratorio 2013; 19 (07-08)

Growth hormone deficiency in adults

Builes MCE, Campuzano MG

Language: Spanish
References: 97
Page: 337-352
PDF size: 465.11 Kb.


ABSTRACT

Growth hormone has functions beyond these its name implies. During adulthood, it is an important hormone for lipid and carbohydrate metabolism, it has vital function in non-fasting states and it has a pivotal role in energetic balance of the body. Growth hormone deficiency is a well-known disease in childhood, with established and easily recognizable consequence. In contrast, adult growth hormone deficiency is more difficult to establish than pediatric ones and it can be related with genetic or acquired causes during childhood, it also can be related with acquired causes during adulthood. In recent years, similar to diverse fields of pharmacology, the isolation and synthesis of recombinant human growth hormone has been achieved, which has opened the door for treatment of affected patients. However, many questions remain regarding adult growth hormone deficiency, such as the accurate diagnosis, as well as the real benefits and safety of treatment with human growth hormone. In this review article, a state of art of adult growth hormone deficiency is presented.


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