2020, Number 3
<< Back Next >>
Med Int Mex 2020; 36 (3)
Relation between frailty and hip fracture risk by FRAX® in Mexican elderly
Viveros-García JC, Rivera-Chávez JG, Regalado-Villalobos A, Luna-Torres S, Moreno-Cervantes CA, Torres-Gutiérrez JL
Language: Spanish
References: 30
Page: 285-291
PDF size: 198.32 Kb.
ABSTRACT
Background: Hip fracture is the most serious consequence of osteoporosis, and
many patient who suffer from hip fracture are also frail. The risk prediction tools are
useful and validated in Mexico. Among them, FRAX
® is the most used and it does not
include frailty.
Objective: To determine if there is difference in hip fracture risk calculated by FRAX
®
between frail and non-frail elder patients.
Material and Method: A prospective, observational and descriptive study was
done from May and December 2018, including patients 60 years and older with osteopenia
and osteoporosis. We measured socio-demographical variables, comorbidity,
densitometric results and hip fracture risk by FRAX
®.
Results: We included 221 patients with a mean age of 77 years, mostly women.
There were no statistical difference between hip fracture risk among frail and nonfrail
patients.
Conclusions: Frailty should be considered in the decision making model for hip
fracture risk; predictive tools may underestimate the risk in frail patients.
REFERENCES
Informe Mundial sobre Envejecimiento y Salud. OMS. 2015;(http://ww.
D'Hyver C GRL. Geriatría 2014.
Lovato-Salas F, Luna-Pizarro D, Oliva-Ramírez SA, Flores- Lujano J, Núñez-Enríquez JC. Prevalencia de fracturas de cadera, fémur y rodilla en la Unidad Médica de Alta Especialidad Hospital de Traumatología y Ortopedia del Instituto Mexicano del Seguro Social. Acta Ortop Mex 2015;29(1):13-20. http://pesquisa.bvsalud.org/portal/ resource/pt/mdl-26999921.
Grigoryan KV, Javedan H, Rudolph JL. Ortho-geriatric care models and outcomes in hip fracture patients: A systematic review and meta-analysis. J Orthop Trauma 2014;28(3):49- 55. doi:10.1097/BOT.0b013e3182a5a045.
Holt G, Smith R, Duncan K, Hutchison JD, Reid D. Changes in population demographics and the future incidence of hip fracture. Injury 2009;40(7):722-726. doi:10.1016/j. injury.2008.11.004.
Albavera Gutiérrez RR, López García R, Eduardo C, et al. Mortalidad de pacientes con fractura de cadera a cinco años de evolución en el Hospital Regional General Ignacio Zaragoza. Rev Esp Méd Quir 2013;18(1):31-36.
González-Montalvo JI, Alarcón T, Hormigo Sánchez AI. ¿Por qué fallecen los pacientes con fractura de cadera? Med Clin (Barc) 2011;137(8):355-360. doi:10.1016/j. medcli.2010.07.005.
Morley JE. Frailty, falls, and fractures. J Am Med Dir Assoc 2013;14(3):149-151. doi:10.1016/j.jamda.2012.12.009.
Vasu BK, Ramamurthi KP, Rajan S, George M. Geriatric patients with hip fracture: frailty and other risk factors affecting the outcome. Anesth Essays Res 2018;12(2):546- 551. doi:10.4103/aer.AER_61_18.
Alarcón T, González-Montalvo JI. Fractura de cadera en el paciente mayor. Rev Esp Geriatr Gerontol 2010;45(3):167- 170. doi:10.1016/j.regg.2009.12.003.
Veronese N, Maggi S. Epidemiology and social costs of hip fracture. Injury 2018;49(8):1458-1460. doi:10.1016/j. injury.2018.04.015.
Velasco-Murillo V, Navarrete-Hernández E, Pozos-Cavanzo JL, Ojeda-Mijares RI C-RM. Fracturas en mujeres postmenopáusicas en el IMSS: frecuencia y costos de su atención hospitalaria Vitelio. Gac Med Mex 2003;139(5):453-458. http://www.medigraphic.com/pdfs/gaceta/gm-2003/ gm035d.pdf. Accessed April 19, 2018.
Ensrud KE, Ewing SK, Taylor BC, et al. Frailty and risk of falls, fracture, and mortality in older women: the study of osteoporotic fractures. J Gerontol Ser A Biol Sci Med Sci 2007;62(7):744-751. doi:10.1093/gerona/62.7.744.
Clark P, Ramírez-Pérez E, Reyes-López A. Umbrales de evaluación e intervención para la detección de casos en riesgo de osteoporosis (OP) y fracturas por fragilidad con FRAX® en población mexicana para el primer nivel de salud. Gac Med Mex 2016;152:22-31.
Chen L-Y, Hwang A-C, Lee W-J, et al. Association between frailty, osteoporosis, falls and hip fractures among community-dwelling people aged 50 years and older in Taiwan: Results from I-Lan Longitudinal Aging Study. PLoS One 2015;10(9):e0136968. doi:10.1371/journal. pone.0136968.
Masud T, Binkley N, Boonen S, Hannan MT, FRAX® Position Development Conference Members. Official Positions for FRAX® Clinical Regarding Falls and Frailty: Can Falls and Frailty be Used in FRAX®? J Clin Densitom 2011;14(3):194- 204. doi:10.1016/j.jocd.2011.05.010.
Weblet Importer. https://www.sheffield.ac.uk/FRAX/tool. aspx?country=24. Accessed April 22, 2019.
González Montalvo JI, Gotor Pérez P, Martín Vega A, et al. La unidad de ortogeriatría de agudos. Evaluación de su efecto en el curso clínico de los pacientes con fractura de cadera y estimación de su impacto económico. Rev Esp Geriatr Gerontol 2011;46(4):193-199. doi:10.1016/j. regg.2011.02.004.
Alarcón T, Gonzalez-Montalvo JI, Gotor P, Madero R, Otero A. A new hierarchical classification for prognosis of hip fracture after 2 years’ follow-up. J Nutr Health Aging 2011;15(10):919-923. doi:10.1007/s12603-011-0129-y.
Giangregorio LM, Leslie WD, Lix LM, et al. FRAX underestimates fracture risk in patients with diabetes. J Bone Miner Res 2012;27(2):301-308. doi:10.1002/jbmr.556.
Roux C, Briot K. Imminent fracture risk. Osteoporos Int 2017;28(6):1765-1769. doi:10.1007/s00198-017-3976-5.
Dalle Carbonare L, Giannini S, Sartori L, et al. Lumbar osteoarthritis, bone mineral density, and quantitative ultrasound. Aging Clin Exp Res 2000;12(5):360-365. doi:10.1007/BF03339861.
Morley JE. Pharmacologic options for the treatment of sarcopenia. Calcif Tissue Int 2016;98(4):319-333. doi:10.1007/ s00223-015-0022-5.
Tessier A-J, Chevalier S, Tessier A-J, Chevalier S. An update on protein, leucine, omega-3 fatty acids, and vitamin d in the prevention and treatment of sarcopenia and functional decline. Nutrients 2018;10(8):1099. doi:10.3390/ nu10081099.
Rondanelli M, Klersy C, Terracol G, et al. Whey protein, amino acids, and vitamin D supplementation with physical activity increases fat-free mass and strength, functionality, and quality of life and decreases inflammation in sarcopenic elderly. Am J Clin Nutr 2016;103(3):830-840. doi:10.3945/ajcn.115.113357.
Nieves JW. Calcium, vitamin D, and nutrition in elderly adults. Clin Geriatr Med 2003;19(2):321-335. doi:10.1016/ S0749-0690(02)00073-3.
Balk EM, Adam GP, Langberg VN, et al. Global dietary calcium intake among adults: a systematic review. Osteo poros Int 2017;28(12):3315-3324. doi:10.1007/s00198- 017-4230-x.
Ruggiero C, Zampi E, Rinonapoli G, et al. Fracture prevention service to bridge the osteoporosis care gap. Clin Interv Aging 2015;10:1035-1042. doi:10.2147/CIA.S76695.
Barton DW, Behrend CJ, Carmouche JJ. Rates of osteoporosis screening and treatment following vertebral fracture. Spine J 2019;19(3):411-417. doi:10.1016/J. SPINEE.2018.08.004.
Nguyen ET, Posas-Mendoza T, Siu AM, Ahn HJ, Choi SY, Lim SY. Low rates of osteoporosis treatment after hospitalization for hip fracture in Hawaii. Osteoporos Int 2018;29(8):1827-1832. doi:10.1007/s00198-018- 4553-2.