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2018, Number S1

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Cuba y Salud 2018; 13 (S1)

High alpha-fetoprotein in pregnant women from Artemisa province

Fuentes LT, Herrera AAR, González LN, Pérez TJ

Language: Spanish
References: 24
Page: 380-383
PDF size: 184.93 Kb.


ABSTRACT

Objective: to characterize the relationship of the elevated alpha-fetoprotein in maternal serum with the appearance of congenital defects and obstetric complications in pregnant women of the Artemisa province in the period from January 2011 to December 2013.
Method: a cross-sectional descriptive study was carried out in three municipalities; samples with concentrations of Alfafetoprotein equal to or greater than 2.0 MoM were considered high. The data were obtained from the linear registry of the municipal genetic risk consultations, as well as the annual reports of the Genetics program and processed with descriptive statistics techniques. The established ethical principles were taken into account.
Results: it was found that only 3,5% of pregnant women with high alpha-fetoprotein had a congenital defect. In 84%, no apparent cause was found and of these 42,26% had some obstetric complication.
Conclusions: pregnant women predominated with high alpha-fetoprotein without apparent genetic cause, more defects of the neural tube than of the abdominal wall. Obstetric complications occurred in almost half of the pregnant women studied, low birth weight and preterm birth predominated, which allows us to consider the value of this glycoprotein as a predictor of obstetric complications and useful for the identification of high risk patients.


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