2019, Number 3
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Rev Cent Dermatol Pascua 2019; 28 (3)
Cutaneous loxoscelism
Cardona-Hernández MÁ, Barragán-Dessavre M, Muñoz-de Peña KV, Rodríguez QIC
Language: Spanish
References: 14
Page: 122-126
PDF size: 1084.64 Kb.
ABSTRACT
Loxoscelism term is known as the clinical manifestations presented after the bite of spiders of the genus
Loxosceles reclusa. There are two clinical varieties: the local or cutaneous and the systemic or cutaneous-visceral. The first one is the most common in 80%. In this article we report the case of a patient with a cutaneous variety of loxoscelism, with good response to conventional treatment.
REFERENCES
Dunbar JP, Sulpice R, Dugon MM. The kiss of (cell) death: can venom-induced immune response contribute to dermal necrosis following arthropod envenomations? Clin Toxicol (Phila). 2019; 57: 677-685.
Cabrerizo S, Docampo P, Cari C, Ortiz de Rozas M, Díaz M, de Roodt AR et al. Loxoscelismo: epidemiología y clínica de una patología endémica en el país. Arch Argent Pediatr. 2009; 107: 152-159.
Manríquez JJ, Silva S. Cutaneous and visceral loxoscelism: a systematic review. Rev Chilena Infectol. 2009; 26: 420-432.
Anoka IA, Robb EL, Baker MB. Brown recluse spider toxicity. Stat pearls [Internet]. Treasure Island (FL): Stat Pearls Publishing; 2018-2019. https://www.ncbi.nlm.nih.gov/books/NBK537045
Hurtado-Valenzuela JG, Sotelo-Cruz N, Ibarra-Silva R. Envenenamiento por Loxosceles reclusa (araña “parda”). Rev Mex Pediatr. 2005; 72: 85-88.
Jerusalem K, Salavert Lletí M. Probable cutaneous loxoscelism with mild systemic symptoms: a case report from Spain. Toxicon. 2018; 156: 7-12.
Andersen RJ, Campoli J, Johar SK, Schumacher KA, Allison EJ Jr. Suspected brown recluse envenomation: a case report and review of different treatment modalities. J Emerg Med. 2011; 41: e31-e37.
Tambourgi DV, Gonçalves-de-Andrade RM, van den Berg CW. Loxoscelism: from basic research to the proposal of new therapies. Toxicon. 2010; 56: 1113-1119.
Calabria PAL, Shimokava-Falcao LHAL, Colombini M, Moura-da-Silva AM, Barbaro KC, Faquim-Mauro EL et al. Design and production of a recombinant hybrid toxin to raise protective antibodies against Loxosceles spider venom. Toxins (Basel). 2019; 11. pii: E108. doi: 10.3390/toxins11020108.
Tambourgi DV, Paixão-Cavalcante D, Gonçalves de Andrade RM, Fernandes-Pedrosa Mde F, Magnoli FC, Paul Morgan B et al. Loxosceles sphingomyelinase induces complement-dependent dermonecrosis, neutrophil infiltration, and endogenous gelatinase expression. J Invest Dermatol. 2005; 124: 725-731.
Lopes PH, Murakami MT, Portaro FCV, Mesquita-Pasqualoto KF, van den Berg C, Tambourgi DV. Targeting Loxosceles spider sphingomyelinase D with small-molecule inhibitors as a potential therapeutic approach for loxoscelism. J Enzyme Inhib Med Chem. 2019; 34: 310-321.
Albuquerque PLMM, Tessarolo LD, Menezes FH, Lima TB, Paiva JHHGL, Silva Júnior GBD et al. Acute kidney injury due to systemic Loxoscelism: a cross-sectional study in Northeast Brazil. Rev Soc Bras Med Trop. 2018; 51: 695-699.
Stoecker WV, Vetter RS, Dyer JA. NOT RECLUSE-a mnemonic device to avoid false diagnoses of brown recluse spider bites. JAMA Dermatol. 2017; 153: 377-378.
Cristina de Oliveira-Lima K, Farsky SH, Lopes PH, de Andrade RM, van den Berg CW, Tambourgi DV. Microcirculation abnormalities provoked by Loxosceles spiders’ envenomation. Toxicon. 2016; 116: 35-42.