2019, Number 5
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Mul Med 2019; 23 (5)
Depressive disorders and vital events in patients with arterial hypertension and its relationship with therapeutic adherence
Vázquez MA, Mukamutara J, Meireles OMY, Vázquez AL
Language: Spanish
References: 19
Page: 1079-1094
PDF size: 163.91 Kb.
ABSTRACT
Introduction: arterial hypertension (hypertension) is one of the great challenges of modern medicine, due to its high prevalence, it is probably the most important health problem in developed and underdeveloped countries. It affects about one billion adults and according to projections by 2025 there will be 1.5 million people with the disease, which is equivalent to 30% of the world's population.
Objective: to identify the presence of depressive disorders and vital events in patients with arterial hypertension and their relationship with adherence to antihypertensive therapy.
Method: a descriptive, cross-sectional study was conducted with 222 hypertensive patients from the Central Hospital of Nampula, Mozambique. Some sociodemographic variables, depressive symptomatology, psychiatric diagnosis, current vital events and therapeutic adherence were studied. Bivariate analyzes were performed to correlate adherence to treatment with the presence of psychological symptoms, psychopharmacological treatment, vital events and diagnosis of depressive illness.
Results: the frequency of depressive symptoms was 40.5%. The most frequent diagnoses were major depressive disorder, dysthymic disorder and adaptive disorders with depressive mood. Current vital events affected 77.9% of hypertensive patients; the most frequent were the death of loved relatives, suffering from physical illnesses and interpersonal conflicts. 42.8% had poor adherence to antihypertensive medication, which was significantly associated (p <0.05) with the presence of depressive symptoms, need for psychopharmacological treatment, being affected by 3 or more current life events and having Diagnosis of a depressive disorder.
Conclusions: the frequency of depression is high in hypertensive patients and depressed patients have poor therapeutic adherence. Current vital events negatively influence compliance with antihypertensive treatment.
REFERENCES
Berisa HD, Dedefo MG. Non-Adherence Related Factors to Antihypertensive Medications Among Hypertensive Patients on Follow up at Nedjo General Hospital in West Ethiopia. Op Publ Health J 2018; 11: 62–71.
Osamor PE, Owumi BE. Factors Associated with Treatment Compliance in Hypertension in Southwest Nigeria. J Health Popul Nutr 2011; 29(6): 619–28.
Rantanen AT, Antero Korkeila JJ, Löyttyniemi ES, Maria Saxén UK, Korhonen PE. Awareness of hypertension and depressive symptoms: a cross-sectional study in a primary care population. Scand J Prim Health Care 2018; 36(3): 323–8.
Hu B, Liu X, Yin S, Fan H, Feng F, Yuan J. Effects of Psychological Stress on Hypertension in Middle-Aged Chinese: A Cross-Sectional Study. PLoS ONE 2015; 10(6): e0129163.
Ajayi IO, Sowemimo IO, Akpa OM, Ossai NE. Prevalence of hypertension and associated factors among residents of Ibadan-North Local Government Area of Nigeria. Nig J Cardiol 2016; 13(1): 67–75.
Macquart de Terline D, Kane A, Kramoh KE, Toure IA, Mipinda JB, Diop IB, et al. Factors associated with poor adherence to medication among hypertensive patients in twelve low and middle income Sub-Saharan countries. PLoS ONE 2019; 14(7): e0219266.
Bautista LE, Vera-Cala LM, Colombo C, Smith P. Symptoms of depression and anxiety and adherence to antihypertensive medication. Am J Hypertension 2012; 25(4): 505–11.
Zhanzhan L, Yanyan L, Lizhang C, Peng C, Yingyun H. Prevalence of Depression in Patients With Hypertension: A Systematic Review and Meta-Analysis. Medicine 2015; 94(31): e1317.
Kretchy IA, Owusu-Daaku FT, Danquah SA. Mental health in hypertension: assessing symptoms of anxiety, depression and stress on anti-hypertensive medication adherence. Internat J Ment Health Syst 2014; 8: 25–37.
Krousel-Wood MA, Frohlich ED. Hypertension and Depression: Co-existing Barriers to Medication Adherence. J Clin Hypertens 2010; 12(7): 481–6.
Mahmood S, Hassan SZ, Tabraze M, Khan MO, Javed I, Ahmed A, et al. Prevalence and Predictors of Depression Amongst Hypertensive Individuals in Karachi, Pakistan. Cureus 2017; 9(6): e1397.
Ashok VG, Ghosh SS. Prevalence of Depression among Hypertensive Patients Attending a Rural Health Centre in Kanyakumari. Natl J Community Med 2019; 10(3): 172–5.
Hamrah MS, Hamrah MH, Ishii H, Suzuki S, Hamrah MH, Hamrah AE, et al. Anxiety and Depression among Hypertensive Outpatients in Afghanistan: A Cross-Sectional Study in Andkhoy City. Internat J Hypertension [Internet]. 2018 [citado 5/1/2019]: 8p. Disponible en: https://www.hindawi.com/journals/ijhy/2018/8560835/ 14. Prathibha MT, Varghese S, Gokul DV, Jincy J. Prevalence of depression among hypertensive individuals in urban Trivandrum: a cross sectional study. Int Community Med Publ Health 2017; 4(6): 2156–61.
Boima V, Ademola AD, Odusola AO, Agyekum F, Nwafor CE, Cole H, et al. Factors Associated with Medication Nonadherence among Hypertensives in Ghana and Nigeria. Internat J Hypertension [Internet]. 2015 [citado 5/1/2019]: 8p. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4610060/
16.Neupane D, Panthi B, McLachlan CS, Mishra SR, Kohrt BA, Kallestrup P. Prevalence of Undiagnosed Depression among Persons with Hypertension and Associated Risk Factors: A Cross-Sectional Study in Urban Nepal. PLoS ONE 2015; 10(2): e0117329.
Zakaria N, Baharudin A, Razali R. The effect of depressive disorders on compliance among hypertensive patients undergoing pharmacotherapy. ASEAN J Psychiatr 2009; 10 (2): 1–11.
Lauffenburger JC, Gagne JJ, Song Z, Brill G, Choudhy NK. Potentially disruptive life events: what are the immediate impacts on chronic disease management? A case-crossover analysis. BMJ Open 2016; 6(8): e010958.
Vázquez Machado A. Factores de riesgo psicosociales de hipertensión arterial en una comunidad venezolana. MEDISAN 2014; 18(2): 211–218.
Son YJ, Won MH. Depression and medication adherence among older Korean patients with hypertension: Mediating role of self-efficacy. Internat J Nurs Practice [Internet]. 2017 [citado 5/1/2019]; 23 (3). Disponible en: https://onlinelibrary.wiley.com/doi/full/10.1111/ijn.12525