2020, Number 2
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salud publica mex 2020; 62 (2)
Predictors of kidney function in a cohort of Mexican adults
Torrescano-de Labra EL, Cupul-Uicab LA, Ramírez-Palacios P, Salmerón J, Muñoz-Aguirre CP, Salazar-Martínez E
Language: Spanish
References: 40
Page: 156-165
PDF size: 292.80 Kb.
ABSTRACT
Objectives. Our aim was to examine prospectively predictors
of subclinical renal alterations among adults without
chronic kidney disease.
Materials and methods. We
analyzed data from a cohort of Mexican adults (n=757).
Kidney function (2010) was assessed with the estimated
glomerular filtration rate (eGFR-Cr), serum creatinine and
uric acid. Predictors of each kidney function marker (2004)
were identified with linear and logistic regression models.
Results. 33% had an eGFR-Cr ‹90 ml/min/1.73 m
2. eGFRCr
was lower among men, those ›40 years old and users of
antihypertensive medication; and higher among those with a
high protein intake. Serum creatinine predictors were similar
to those observed for eGFR-Cr. Uric acid decreased in men,
among those with obesity, hypertension and high cholesterol.
Conclusion. Conventional kidney function biomarkers are
useful to identify subclinical alterations. Some predictors of
kidney function are potentially modifiable, therefore susceptible
for intervention among high-risk groups.
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