medigraphic.com
ISSN 1028-4818 (Electronic)

2019, Number 4

<< Back Next >>

Mul Med 2019; 23 (4)

Prognostic evaluation of acute coronary syndrome in patients with metabolic syndrome

Pérez DJA, Boza TPE, Del Castillo SI, Cervantes CLF, Sánchez SA, Pérez OA

Language: Spanish
References: 18
Page: 685-698
PDF size: 694.57 Kb.


ABSTRACT

Introduction: metabolic syndrome increases the risk for cardiovascular disease and doubles mortality.
Objective: to identify the prognostic factors of death due to acute coronary syndrome in patients with metabolic syndrome.
Method: a cohort analytical observational study was conducted in 186 patients with acute coronary syndrome admitted between 01 February 2015 and 20 October 2018. Clinical and epidemiological variables were included; the strength of association between the qualitative variables and the risk of developing death due to acute coronary syndrome in the presence of metabolic syndrome with Odds Ratio with 95% confidence interval was evaluated. Multivariate analysis was performed using the Cox logistic regression model.
Results: the prevalence of the metabolic syndrome was 45.7%, with a mean age of 60.6 years; Female sex and age group over 61 years doubled the risk in a non-significant way. Left ventricular hypertrophy, heart failure and atrial fibrillation increased the risk of the appearance of a statistically significant acute coronary syndrome in the presence of the metabolic syndrome, p, 000. Moderate to severe left ventricular dysfunction [OR 5.7 95% CI (1,115-5,961) p, 000], Killip-Kimball class ≥II [OR 7.9 IC 95% (3, 10-20, 15) p, 000] and infarction without ST elevation [OR 2.970 95% CI (1.174-7.518) p, 000], were significantly related to death.
Conclusions: metabolic syndrome increases the risk of suffering acute coronary syndrome and death but it is not significantly related to survival.


REFERENCES

  1. Fonte Medina N, Sanabría Negrín JG, Bencomo Fonte LM, Fonte Medina A, Rodríguez Negreria IL. Factores de riesgo asociados y prevalencia de síndrome metabólico en la tercera edad. Rev Cienc Méd de Pinar del Río 2014; 18(6): 963-973.

  2. Valdés Ramos E, Bencosme Rodríguez N. Síndrome metabólico y enfermedad cardiovascular en personas con diabetes mellitus tipo 2. Rev Cub Endocrinol 2013; 24(2): 125-135.

  3. Fernández-Travieso JC. Síndrome Metabólico y Riesgo Cardiovascular. Rev. CENIC Ciencias Biológicas 2016; 47(2): 106-119.

  4. Bojorges JA, Castillo JA, Jiménez R. Factores de riesgo de síndrome metabólico en estudiantes de la universidad Pablo Guardado Chávez, año 2013. Rev Cubana Investig Biom 2013; 32(4): 379-388.

  5. Bassi N, Karagodin I, Wang S, Vassallo P, Priyanath A, Massaro E, Stone NJ. Lifestyle modification for metabolic syndrome: a systematic review. Am J Med 2014; 127(12): 1242.e1-10.

  6. Calton EK, James AP, Pannu PK, Soares MJ. Certain dietary patterns are beneficial for the metabolic syndrome: reviewing the evidence. Nutr Res 2014; 34(7): 559-568.

  7. Agramonte Martínez M, Barnés Domínguez JA, Pinto Correa MA. Prevalencia del síndrome metabólico en pacientes diabéticos tipo 2. Rev Cubana Med 2009; 48(1): 1-7.

  8. Bell Castillo J, George Carrión W, García Céspedes ME, Delgado Bell E. Identificación del síndrome metabólico en pacientes con diabetes mellitus e hipertensión arterial. MEDISAN 2017; 21(10): 3038-45.

  9. Olijhoek JK, Van der Graaf Y, Banga JD, Algra A, Rabelink TJ, Visseren FL. The metabolic syndrome is associated with advanced vascular damage in patients with coronary heart disease, stroke, peripheral arterial disease or abdominal aortic aneurysm. Eur Heart J 2004; 25(4): 342-348.

  10. Madrid-Miller A, Alcaraz-Ruiz A, Borrayo-Sánchez, G, Almeida-Gutiérrez E, Vargas-Guzmán RM, Jáuregui-Aguilar R. Síndrome Metabólico, impacto clínico y angiografíco en pacientes con Síndrome Coronario Agudo. Cir Cir 2010; 78(2): 115- 123.

  11. Consenso Latinoamericano de la Asociación Latinoamericana de Diabetes. Epidemiología, diagnóstico, control, prevención y tratamiento del síndrome metabólico en adultos. Rev Asoc Latinoam Diab. 2010; 18(1): 25-44.

  12. Tzorin P, Castellanos A, Chopox L, Arenas A, Ortiz D. Frecuencia de Síndrome Metabólico en personal de mantenimiento que labora dentro del campus central de la Universidad de San Carlos de Guatemala, en el año 2014. Rev Cientif de la Facultad de Ciencias Químicas y Farmacia 2015; 24(1): 9-17.

  13. Lizarzaburu Robles JC. Síndrome metabólico: concepto y aplicación práctica. An Fac med 2013; 74(4): 315-20.

  14. Contreras F, Hernández P, Mata C, Hernández C. Síndrome metabólico y diabetes mellitus tipo 2 en población adulta. Los salías, Edo. Miranda-Venezuela. Síndrome Cardiometabólico 2015; 5(1): 19-23.

  15. Won KB, Chang HJ, Kim HC, Jeon K, Lee H, Shin S, et al. Differential impact of metabolic syndrome on subclinical atherosclerosis according to the presence of diabetes. Cardiovasc Diab 2013; 12: 41.

  16. Jover A, Corbella E, Muñoz A, Millán J, Pintó X, Mangas A, et al. Prevalencia del síndrome metabólico y de sus componentes en pacientes con síndrome coronario agudo. Rev Esp Cardiol 2011; 64(7):579–86.

  17. Piombo AC, Gagliardi J, Blanco F, Crotto K, Ulmete E, Guetta J, et al. Prevalencia, características y valor pronóstico del síndrome metabólico en los síndromes coronarios agudos. Rev Arg Cardiol 2005; 73(6): 424-428.

  18. Global, Regional, and National Burden of Cardiovascular Diseases for 10 Causes, 1990 to 2015. J Am Coll Cardiol 2017; 70(1):1-25.




2020     |     www.medigraphic.com