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2020, Number 03

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Revista Médica Sinergia 2020; 5 (03)

Hidradenitis suppurativa: literature review

Quesada MC, Fung FMP, Medina CNV
Full text How to cite this article

Language: Spanish
References: 16
Page: 367-367
PDF size: 139.73 Kb.


Key words:

hidradenitis suppurativa, skin diseases, dermatology.

ABSTRACT

Hidradenitis suppurativa or reverse acne is a chronic inflammatory disease of the skin that affects the terminal follicular epithelium of the apocrine glands characterized by the recurrent appearance of nodules, fistulous pathways or purulent abscesses typically in intertriginous areas. Its diagnosis is clinical, including primary and secondary criteria, as well as the possibility of performing a biopsy for differential diagnosis. The etiology is not clearly established, and mechanisms of immune deregulation, genetic predisposition, smoking and obesity are postulated, also associates various diseases such as: inflammatory bowel disease, pyoderma gangrenosum, polycystic ovary syndrome, among others, so it could even be classified as a systemic disease. Treatment options include pharmacological, nonpharmacological and surgical therapy and it should be appropriate, a late treatment can occur with sequelae in the form of fistulas and extensive scars that affect the psychosocial sphere of the patient, limiting thus their quality of life.


REFERENCES

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  2. Vinkel C, Thomsen S. Hidradenitis suppurativa: Causes, features, and current treatments. J Clin Aesthet Dermatol. 2018;11(10):17–23. PDMI: 30519375

  3. Frew J, Hawkes J, Krueger J. Topical, systemic and biologic therapies in hidradenitis suppurativa: pathogenic insights by examining therapeutic mechanisms. Ther Adv Chronic Dis. 2019;10:1–24. https://doi.org/10.1177/2040622319830646

  4. Ingram J, Jenkins-Jones S, Knipe D, Morgan C, Cannings-John R, Piguet V. Population-based Clinical Practice Research Datalink study using algorithm modelling to identify the true burden of hidradenitis suppurativa. Br J Dermatol. 2018;178(4):917–24. https://doi.org/10.1111/bjd.16101

  5. Scuderi N, Monfrecola A, Dessy L, Fabbrocini G, Megna M, Monfrecola G. Medical and Surgical Treatment of Hidradenitis Suppurativa: A Review. Ski Appendage Disord. 2017;3(2):95–110. https://doi.org/10.1159/000462979

  6. Napolitano M, Megna M, Timoshchuk E, Patruno C, Balato N, Fabbrocini G, et al. Hidradenitis suppurativa: From pathogenesis to diagnosis and treatment. Clin Cosmet Investig Dermatol. 2017;10:105– 15. https://doi.org/10.2147/CCID.S111019

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  10. Hunger R, Laffitte E, Läuchli S, Mainetti C, Mühlstädt M, Schiller P, et al. Swiss Practice Recommendations for the Management of Hidradenitis Suppurativa/Acne Inversa. Dermatology. 2017;233(2–3):113–9. https://doi.org/10.1159/000477459

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  13. Patel Z, Hoffman L, Buse D, Grinberg A, Afifi L, Cohen S, et al. Pain, Psychological Comorbidities, Disability, and Impaired Qualify of Life in Hidradenitis Suppurativa. Curr Pain Headache Rep. 2017;21(12):1–14. https://doi.org/10.1007/s11916-017-0647-3

  14. Koumaki D, Efthymiou O, Bozi E, Katoulis A. Perspectives on perceived stigma and self-stigma in patients with hidradenitis suppurativa. Clin Cosmet Investig Dermatol. 2019;12:785–90. https://doi.org/10.2147/CCID.S180036

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Revista Médica Sinergia. 2020;5