2019, Number 2
Hemorragia de tubo digestivo alto no variceal en pacientes con cirrosis hepática
Language: Spanish
References: 13
Page: 97-103
PDF size: 264.93 Kb.
ABSTRACT
Objective: Th e main etiology of upper digestive tract hemorrhage in patients with liver cirrhosis is of variceal origin, as it is a complication characteristic of this disease, the presence of esophageal varices can be found up to 50% of patients with liver cirrhosis at the time of diagnosis. Similarly, the presence of non-variceal upper digestive tract hemorrhage has been described in 30 to 40% of these patients, with mortality rates of 6 to 15%, with peptic ulcer disease being the main etiology. Based on these fi gures, non-variceal upper digestive tract hemorrhage in cirrhotic patients is frequent and its fi gures may be underestimated. Material and methods: Transversal study. We included data from 195 patients diagnosed with CH and HTDA greater than 16 years, without fi rst receiving care or management in another hospital, admitted to the gastroenterology service of the Civil Hospital “Fray Antonio Alcalde” from October 2015 to December 2017. Results: Of 195 patients, 148 (41.8%) were male and 120 (61.5%) Child- Pugh B. The etiology of upper gastro intestinal bleeding was variceal in 144 (73.8%) and nonvariceal in 51 (26.2%) patients, in which the main cause was peptic ulcer disease. 13 (6.6%) patients died, 2(1%) required surgery, 32 (16.4%) had acute renal failure and 25 (12.8%) required more than 4 erythrocyte concentrates. Conclusions: Despite being variceal upper gastrointestinal bleeding more common in patients with hepatic cirrhosis, it is important to diagnose those with nonvariceal etiology, due to the implications in the management and possible emergency endoscopic interventions.REFERENCES
Villanueva Sánchez C, García Pagan JC, Hervas Molina AJ. Hemorragia gastrointestinal. Práctica Clínica en Gastroenterología y Hepatología Sección II - Síndromes relevantes en hepato-gastroenterología. Madrid, España. Asociación Española de Gastroenterología. 2015. 1069 páginas. Disponible: www.aegastro.es.
González-González JA, García-Compeán D, Vázquez-Elizondo G, Garza-Galindo A, Jáquez-Quintana JO, Maldonado-Garza H. Nonvariceal upper gastrointestinal bleeding in patients with liver cirrhosis. Clinical features, outcomes and predictors of inhospital mortality. A prospective study. Annals of Hepatology. 2011;10(3):287-295.