2019, Number 2
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Rev Cub de Reu 2019; 21 (2)
Osteomalacia. Diagnosis and treatment
Mendoza MJF, Moreno VMÁ, León DJV, Patiño AMA, Bejarano PFX
Language: Spanish
References: 15
Page: 1-11
PDF size: 137.78 Kb.
ABSTRACT
Introduction: osteomalacia is characterized by the lack of mineralization of the osteoid substance, which affects cortical bone and mature cancellous bone. It is a disease that occurs in adults and children, although the cause is different in each.
Objective: to expose the generality of osteomalacia for being a disease that causes serious affectations to the population that suffers it, especially to children. Emphasis is placed on the diagnosis and its treatment.
Development: in order to summarize the essential elements to establish the diagnosis of osteomalacia, we must first consider the presence of a bone mineralization disorder, hence, in addition to taking into account the causes of the disease, its clinical course and the symptomatology.
Conclusions: an important recommendation is not to take into account the possibility of complications in the course of the disease, such as fractures, which, although they are part of the clinical picture, can cause serious problems when they occur, as in the case of those that appear in the ribs, which if they move may involve vital organs, so that in this type of patients should not exclude the possibility of emergencies or rheumatological emergencies in both adults and children.
REFERENCES
Kraenzlin M. Ostéomalacie. Forum Med Suisse 2003;32:754-63.
Peris P. Osteomalacia. En: Farreras P, Rozman C, editores. Farreras-Rozman. Medicina interna. 16.a ed. Madrid: Elsevier; 2009. pp. 1085-8.
Bonilla Hernán M G. Osteomalacia. En: Arboleya Rodriguez L, Pérez Edo L, directores. Manual de Enfermedades Óseas (SER). 2ª ed. Madrid: Médica Panamericana. 2010. pp. 381-87.
Peris P. Diagnóstico y tratamiento de la osteomalacia por el reumatólogo. Reumatol Clin. 2011;7(S2):S22-S27.
Doreen G. Le calcium santé des dents. Station de recherche Agroscope Liebefeld-Posieux ALP. Berne:2009.
Perris P. Diagnóstico y tratamiento de la osteomalacia por el reumatólogo. Reumatol Clin. 2011;7(S2):S22-S27.
Chapuy MC, Arlot ME, Duboeuf F, Brun J, Crouzet B, Arnaud S, Meunier PJ . Vitamin D3 and calcium to prevent hip fractures in the elderly women. N Engl J Med. 1992;327(23):1637-42.
Trivedi DP, Doll R, Khaw KT. Effect of four monthly oral vitamin D3 supplementation on fractures and mortality in men and women living in the community: randomized double blind controlled trial. BMJ. 2003;326(7387):469.
Lamy O, Aubry-Rozier B, Stoll D. Therapeutic goal of vitamin D: optimal serum level and dose requirements. Rev Med Suisse. 2012;8:2066-71.
Ruiz-Esquide V, Peris P, Gifre L, Guañabens N. Alteraciones del metabolismo óseo en la cirugía bariátrica. Med Clin (Barc). 2011;136:215-21.
Stoll D, So A, Krieg MA, Aubry-Rozier B. High prevalence of hypovitaminosis D in a Swiss rheumatology outpatient population. Swiss Med Wkly. 2011;141(2122).
Gallagher JC1, Sai A, Templin T 2nd, Smith L. Dose response to vitamin D supplementation in postmenopausal women: a randomized trial. Ann Intern Med 2012; 156:425-37.
Laroche M. Failure of teriparatide in treatment of bone complications of adult hypophosphatasia. Calcif Tissue Int. 2012;90(3):250.
Bhadada SK, Dhiman V, Mukherjee S, Aggarwal S, Bal A, Sukumar SP, Van Hul W. Fibrogenesis Imperfect Ossium and Response to Human Growth Hormone: A Potential Therapy. J Clin Endocrinol Metab 2017;102:1750-56.
Arturi A, Arturi V, Giacomone D. Emergencias y urgencias en Reumatología clínica. Revista Argentina de Reumatología 2017;28(4):35-41.