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2019, Number 2

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Rev Cubana Neurol Neurocir 2019; 9 (2)

Prognostic factors in the surgery of the temporal lobe refractory epilepsy

Grave PKA, Bender BJE, Morales CLM

Language: Spanish
References: 28
Page: 1-19
PDF size: 503.36 Kb.


ABSTRACT

Objective: To identify the clinical, imaging and electroencephalographic (EEG) factors that have a predictive value in the postoperative evolution of lobectomized patients with refractory temporal lobe epilepsy.
Methods: Descriptive, longitudinal, retrospective clinical study of 30 patients affected by temporal lobe refractory epilepsy, subjected to lobectomy at the International Neurological Restoration Center, from January 2002 to December 2013. Clinical, imaging and electroencephalographic variables were used. For data statistical analysis, the programs SPSS version 15.0, Win Bugs 3.0.3 and Epidat 3.0 were used.
Results: It was found that 50 % of patients presented their first crisis after 2 years of surgery. No statistically significant association was detected with the presence of structural lesions by magnetic resonance. Patients with no injuries have a crisis faster and in greater proportion. Having unilateral epileptiform activity in the electroencephalogram was detected as a poor prognostic factor. Additionally, there was a significant change in the electroencephalogram at six months and one year of evolution, with respect to the initial evaluation.
Conclusions: Personal antecedents of illness, absence of psychiatric disorders and absence of epileptic status were identified with unfavorable prognostic value. Favorable prognostic value were identified in the right lobectomy patients and groups I-II of the Engel classification per year.


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