2020, Number 1
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salud publica mex 2020; 62 (1)
Population impact of rotavirus vaccination in Mexico after 10 years
Richardson-López CV, Bautista-Márquez A, Sánchez-Uribe E, Esparza-Aguilar M
Language: Spanish
References: 25
Page: 6-13
PDF size: 431.05 Kb.
ABSTRACT
Objective. To evaluate the impact of rotavirus (RV) vaccination
after 10 years of it´s universalization on morbidity and
mortality from Acute Diarrheal Disease (ADD) in mexican
children under five years of age.
Materials and methods.
Annual median numbers for ADD new cases, hospitalizations
and deaths were compared between pre and post universalization
periods; absolute and relative reductions were
calculated, considering
p‹0.05 values as significant.
Results.
Mortality, hospitalizations and new cases from ADD in children
under five decreased 52.6, 46, and 15.5% respectively,
in the posuniversalization period. During rotavirus seasons,
reduction in mortality, hospitalizations and new cases was
66.9, 64.7, and 28.7% respectively.
Conclusions. As of the
universal introduction of RV vaccination in Mexico, significant
and sustained reductions are appreciated for mortality and
hospitalizations from ADD, less so for incidence. A most
prominent effect is observed during the winter season.
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