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ISSN 0185-6014 (Print)
Órgano oficial de difusión de la Federación Mexicana de Patología Clínica, AC y de la Asociación Latinoamericana de Patología Clínica/Medicina de Laboratorio

2019, Number 4

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Rev Mex Patol Clin Med Lab 2019; 66 (4)

Optimization of blood volume in laboratory tests (blood cytometry, coagulation times and factor quantification) in pediatric patients

Parra-Ortega I, López-Valladares K, De la Rosa-Martínez G, Ramírez-Malagón R, Viveros-Rodríguez RT, Vázquez-Gil A, López-Martínez B

Language: Spanish
References: 17
Page: 212-220
PDF size: 366.45 Kb.


ABSTRACT

Introduction: In pediatric patients with serious or complex diseases, there is great difficulty in obtaining optimal blood volumes. For the above reasons, clinical laboratories have found it necessary to modify their procedures for taking and processing blood samples in order to optimize the performance of biological products. Material and methods: This is a prospective, descriptive and comparative study of the results obtained in the determinations of blood cytometry, TP, TTPa and quantification of fibrinogen, coagulation factors V and VII. Results: A multivariate analysis of variance or MANOVA was performed for ICS and patients, obtaining the following values: ICS a value of F = 1.1416 with p = 0.0711 and for patients F = 1.8519 and p = 0.0693 and in the comparison of means (Student t test), there is no difference between the results of the tests of TP, TTPa, quantification of fibrinogen and coagulation factors V and VII taken in the different tubes with sodium citrate. Conclusions: It is possible to use the sampling tubes interchangeably (blood cytometry, coagulation times and quantification of coagulation factors) of the BD Vacutainer® versus Sarstedt® brands since the results are very similar and do not show differences with statistical significance.


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