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Anales de Otorrinolaringología Mexicana

2019, Number 4

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Otorrinolaringología 2019; 64 (4)

Temporal bone malignancies experience

Bigorra-Hevia E, Rocha-Remón P, Morales-Hechevarría PP

Language: Spanish
References: 28
Page: 177-187
PDF size: 348.27 Kb.


ABSTRACT

Objective: To describe the clinical-epidemiological behavior and therapeutic management of the temporal bone malignancies in patients treated at the National Institute of Oncologia and Radiobiology, Cuba.
Material and Method: A descriptive, longitudinal, retrospective study was performed from January, 2002 to December, 2012. The variables such as: age, sex, skin color, initial symptom, histology, initial location, extension, clinical stage, surgical technique, therapeutic modality, surgical complications and survival at 60 months were developed using descriptive statistic.
Results: There were included 28 clinical charts. The group of age of 55-67 years was the most representative (35.6%). The 71.4% were males and the 89.1% were Caucasian. The 53.6% presented with chronic otorrhea. The squamous cell carcinoma prevailed with 67.8%. The initial location was the external auditory canal with 82.1% and confined to the origin site in 53.6%. The lateral temporal bone resection was the mainly practiced treatment with 28.5% and surgery plus radiotherapy in 35.6%. The infection of the surgical wound was seen in 7.1% of the cases and the 5 years overall survival was of 77.8%.
Conclusions: The temporal bone malignancies were more frequent between sixthseventh decade in Caucasian males. Otorrea was the main symptom, prevailing the squamous cell carcinoma located at the external auditory canal and confined to the origin site. Five years overall survival was of 77.8%.


REFERENCES

  1. Peele JC, Hauser CH. Primary carcinoma of the external auditory canal and middle ear. Arch Otolaryngol 1941; 34: 254-266. doi:10.1001/archotol. 1941.00660040280003

  2. Stell PM, McCormick MS. Carcinoma of the external auditory meatus and middle ear: prognostic factors and a suggested staging system. J Laryngol Otol 1985;99:847-850. DOI: 10.1017/s0022215100097796

  3. Newhart H. Primary carcinoma of the middle ear: report of a case. Laryngoscope 1917;27:543-555. https://doi. org/10.1288/00005537-191707000-00002

  4. Parsons H, Lewis JS. Subtotal resection of the temporal bone for cancer of the ear. Cancer 1954;7:995-1001. https:// doi.org/10.1002/1097-0142(195409)7:5%3C995::AIDCNCR2820070524% 3E3.0.CO;2-A

  5. Janecka IV, et al. Surgical management of temporal bone cancer. Head and Neck Cancer, Lippincott-Raven- Publishers, 1997.

  6. Martín Esborrat L. Cáncer de hueso temporal. Ed 1. p 26, 2000.

  7. Diamante V, Marengo R, Haddad J, Hernández J. Cáncer de hueso temporal. Actualización, estadificación topovolumétrica y técnica quirúrgica indicada. Revista de ORL de la Fundación de otorrinolaringología 1996;12(25).

  8. Morton RP, Stell PM, Derrick PP. Epidemiology of cancer of the middle ear. Cancer 1984;53:1612-1617. DOI: 10.1002/1097-0142(19840401)53:7<1612::aidcncr2820530733> 3.0.co;2-p

  9. Yin M, et al. Analysis of 95 cases of squamous cell carcinoma of the external and meddle ear. Auris Nasus Larynx 2006;33:251-257. DOI: 10.1016/j.anl.2005.11.012

  10. Testa JR, Fukuda Y, Kowalski LP. Prognostic factors in carcinoma of the external auditory canal. Arch Otolaryngol Head Neck Surgery 1997;123:720-4. DOI: 10.1001/archotol. 1997.01900070064010

  11. Kuhel WI, Hume CR, Selesnick SH. Cancer of the external auditory canal and temporal bone. Otolaryngol Clin North Am 1996;29:827-852.

  12. Verge González JC, Contreras Molina P, et al. Middle ear carcinoma. Report of two cases and review of the literature. Hospital Clínico Universitario Virgen de la Victoria. Málaga. Servicio de Otorrinolaringología. ORL Aragón 2009;12(2):6-8.

  13. Colectivo de autores. Registro Nacional de Cáncer. La Habana. 2012.

  14. Cánepa HJ. Comunicación personal. Ed 1. Argentina. 2010.

  15. Mazzoni A, Danesi G, Zanoletti E. Primary squamous cell carcinoma of the external auditory canal: surgical treatment and long-term outcomes. Acta Otorhinolaryngol Ital 2014;34:129-137.

  16. Arriaga M, Curtin H, et al. Staging proposal for external auditory meatus carcinoma based on preoperative clinical examination and computed tomography findings. Ann Otol Rhinol Laryngol 1990;99:714-21. DOI: 10.1177/000348949009900909

  17. Moody SA, Hirsch BE, Myers EN. Squamous cell carcinoma of the external auditory canal: an evaluation of a staging system. Am J Otol 2000;21:582-8.

  18. Lobo D, Llorente JL, Suárez C. Squamous cell carcinoma of the external auditory canal. Skull Base 2008;18:167-72. doi: 10.1055/s-2007-994290

  19. Miller ME, et al. Temporal bone verrucous carcinoma: Outcomes and treatment controversy. Eur Arch Otorhinolaryngol 2010 Dec;267(12):1927-1931. doi: 10.1007/ s00405-010-1281-4

  20. Zanoletti E, Marioni G, et al. Temporal bone squamous cell carcinoma: analyzing prognosis with univariate and multivariate models. Laryngoscope 2014 May;124(5):1192-8. doi: 10.1002/lary.24400.

  21. Leong SC, et al. Squamous cell carcinoma of the temporal bone: outcomes of radical surgery and postoperative radiotherapy. Laryngoscope 2013 Oct;123(10):2442-8. doi: 10.1002/lary.24063.

  22. Gurgel RK, Karnell LH, Hansen MR. Middle ear cancer. A population-based study. Laryngoscope 2009 Oct;119(10):1913-7. doi: 10.1002/lary.20202.

  23. Rodríguez Paramás A, Gil Carrasco R, Arenas Britez O, Scola Yurrita B. Tumores malignos del conducto auditivo externo y oído medio. Acta Otorrinolaringol Esp 2004;55:470-474. https://doi.org/10.1016/S0001-6519(04)78556-8

  24. Sánchez HR. Alteraciones genético-moleculares en el carcinoma epidermoide de oído externo. Universidad de Oviedo, Asturia. Tesis doctoral.

  25. Conley J. Cancer of the middle ear. Ann Otol Rhinol Laryngol 1965;74:555-572. DOI: 10.1177/000348946507400222

  26. Ihler F, Koopmann M, Weiss BG, et al. Surgical margins and oncologic results after carcinoma of the external auditory canal. Laryngoscope 2015 Sep;125(9):2107-12. doi: 10.1002/lary.25381.

  27. Gidley P, Roberts DB, Sturgis EM. Squamous cell carcinoma of the temporal bone. Laryngoscope 2010 Jun;120(6):1144- 51. doi: 10.1002/lary.20937.

  28. Ugumori T, Hyodo J, Hato N, et al. survival in primary carcinoma of the external and middle ear is strongly dependent on stage at diagnosis. Int J Otolaryngol Head Neck Surg 2013;2:221- 227. http://dx.doi.org/10.4236/ijohns.2013.26046




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