2019, Number 3
Frequency and etiology of enteroparasitosis in patients with human immunodeficiency virus at a hospital of Lambayeque, Peru
Language: Spanish
References: 21
Page: 418-427
PDF size: 583.72 Kb.
ABSTRACT
Introduction: Despite antiretroviral therapy, it is still common to find the presence of opportunistic infections such as enteroparasites, which cause a big impact on the health and economy of patients. Objetive: To determine the frequency, etiology and factors associated with enteroparasitosis in patients with HIV at a reference hospital in Lambayeque, Peru. Material and Methods: A prospective observational study was conducted in diarrheic patients with HIV infection in a hospital in Lambayeque from January to June, 2016. The study was a census. Both the collection and transport as well as the analysis of the samples followed the recommendations of the Manual of procedures for the diagnosis of human parasitosis of the National Institute of Health. Results: The meadian age was 28 years, the male sex predominated, and the percentage of parasitism was 73.08%. Patients with viral load >1000 were 69.2% and patients with HAART were 55.8%. Blastocystis hominis was the most frequent parasite (30.77%), followed by Cryptosporidium spp. and Cystoisospora belli with 21.2% and 11.5%, respectively. The bivariate analysis between viral load and HAART with parasitism, demonstrated an association with parasitism. Conclusions: Enteroparasitosis is frequent in patients with HIV and diarrhea, predominating opportunistic infections over non opportunistic ones.REFERENCES
Álvarez Barreneche MF, Restrepo Castro CA, Hidrón Botero A, Villa Franco JP, Trompa Romero IM, Restrepo Carvajal L, et al. Hospitalization causes and outcomes in HIV patients in the late antiretroviral era in Colombia. AIDS Res Ther [Internet]. 2017 Nov [cited 17/08/2018]; 14(1):60. Available from: http://www.ncbi.nlm.nih.gov/pubmed/2913240 0
Agudelo-Gonzalez S, Murcia-Sanchez F, Salinas D, Osorio J. Infecciones oportunistas en pacientes con VIH en el hospital universitario de Neiva, Colombia. 2007-2012. Infectio [Internet]. 2015 Apr [citado 17/08/2018]; 19(2):52–9. Disponible en: https://www.sciencedirect.com/science/article/ pii/S0123939214000721
Suthar AB, Granich R, Mermin J, Annelies &, Rie V. Systematic reviews Effect of cotrimoxazole on mortality in HIV-infected adults on antiretroviral therapy: a systematic review and meta-analysis. Bull World Heal Organ. [Internet]. 2012[cited 17/08/2018]; 90(2):128c–138c. Available from: https://www.ncbi.nlm.nih.gov/pubmed/224231 64
Jha AK, Uppal B, Chadha S, Aggarwal P, Ghosh R, Dewan R. Enteric pathogens, immune status and therapeutic response in diarrhea in HIV/AIDS adult subjects from north India. Curr HIV Res [Internet]. 2013 Jun [cited 12/08/2018];11(4):326–32. Available from: https://www.ncbi.nlm.nih.gov/pubmed/239682 93
Beltran Fabian M, Tello Casanova R, Naquira Velarde C. Manual de procedimientos de laboratorio para el diagnóstico de los parásitos intestinales del hombre. Instituto Nacional de Salud [Internet]. 2003 [citado 17/08/2018]. Disponible en: https://www.google.com/url?sa=t&rct=j&q=&es rc=s&source=web&cd=1&cad=rja&uact=8&ved= 2ahUKEwiV_MTU5cPiAhWv11kKHTPJDYsQFjAAe gQIABAC&url=http%3A%2F%2Fbvs.minsa.gob.pe %2Flocal%2FINS%2F165_NT37.pdf&usg=AOvVa w2CcvsWYAI6Js4omYMSepGN
Silva-Díaz H, Fernández-Valverde D, Hernández-Córdova G, Failoc-Rojas VE. Cystoisospora belli infection in HIV patients: Analysis of cases with different clinical evolution.2013. Rev haban cienc méd [Internet]. 2015 Oct [citado 2019 May 24] ; 14(5):587-598. Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext &pid=S1729-519X2015000500006&lng=es Rev Chil Infectol [Internet]. 2017 [cited 16/08/2018];34(4): 347-351. Available from: https://www.ncbi.nlm.nih.gov/pubmed/291655 11
Silva-Díaz H, Reynoso-Mego A, León- Jiménez F, Failoc-Rojas VE. Clinical and epidemiological characteristics of strongyloidiasis in a hospital in Northern Peru. Infec [Internet]. 2018 [cited 17/08/2018];22(3). Available from: http://www.scielo.org.co/scielo.php?script=sci_ arttext&pid=S0123-93922018000300131
Silva-Díaz H, Monteza-Salazar J, Rentería- Valle CA. Elisa y Examen Microscópico Directo en la Detencción de Giardia en Muestras Fecales de Niños en Chongoyape, Chiclayo, Perú. Rev Exp en Med del Hosp Reg Lambayeque [Internet]. 2015 [citado 16/08/2018];1(1):6–10. Disponible en: http://rem.hrlamb.gob.pe/index.php/REM/articl e/view/5
Chincha O, Bernabé-Ortiz A, Samalvides F, Soto L, Gotuzzo E, Terashima A. Parasite intestinal infection and factors associated with coccidian infection in adults at public hospital in Lima, Peru. Rev Chilena Infectol [Internet]. 2009 Oct [cited 17/08/2018];26(5):440–4. Available from: http://www.ncbi.nlm.nih.gov/pubmed/1991575 4
Silva-Díaz H, Campos-Flores H, Llagas- Linares JP, LLatas-Cancino D. Coccidiosis intestinal en niños admitidos en un hospital de Perú y comparación de dos métodos para la detección del Cryptosporidium spp. Rev Peru Med Exp Salud Pública [Internet]. 2016 Dic [citado 17/08/ 2018];33(4):739–44. Disponible en: https://rpmesp.ins.gob.pe/index.php/rpmesp/ar ticle/view/2560
DaFonseca S, Niessl J, Pouvreau S, Wacleche VS, Gosselin A, Cleret-Buhot A, et al. Impaired Th17 polarization of phenotypically naive CD4(+) T-cells during chronic HIV-1 infection and potential restoration with early ART. Retrovirology. [Internet]. 2015 Apr [cited 17/08/ 2018];12:38. Available from: https://www.ncbi.nlm.nih.gov/pubmed/259248 95