2019, Number 5
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salud publica mex 2019; 61 (5)
Project profile: a multicenter study on breast cancer in young women in Latin America (PRECAMA study)
Romieu I, Biessy C, Torres-Mejía G, Ángeles-Llerenas A, Sánchez GI, Borrero M, Ossa CA, Porras C, Rodríguez AC, Ocampo R, Garmendia ML, Bustamante E, Olivier M, Porter P, Rinaldi S
Language: English
References: 47
Page: 601-608
PDF size: 270.07 Kb.
ABSTRACT
Objective. To describe the rationale and the methodology
of a multicenter project to study the etiology of
breast cancer in young Latin American women.
Materials
and methods. The International Agency for Research
on Cancer has established an international collaborative
population-based case-control study in four countries in
Latin America: Chile, Colombia, Costa Rica, and Mexico
(the PRECAMA study). Standardized methodologies were
developed to collect information on reproductive variables,
lifestyle, anthropometry, diet, clinical and pathological data,
and biological specimens. The study will be extended to
other countries in the region.
Conclusion. PRECAMA is
unique in its multidisciplinary approach that combines genetics,
genomics, and metabolomics with lifestyle factors. The
data generated through this project will be instrumental to identify major risk factors for molecular subtypes of breast
cancer in young women, which will be important for prevention
and targeted screening programs in Latin America.
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