2019, Number 3
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Rev Mex Urol 2019; 79 (3)
Atypical metastases from a renal tumor
Hernández-Alcaraz D, Beneto-Alducin B, Morales-Jiménez P
Language: English
References: 10
Page: 1-14
PDF size: 936.80 Kb.
ABSTRACT
Background: The aim of the present work was to present three clinical
cases with uncommon presentations of metastatic kidney cancer.
Clinical cases: The first case was that of a woman that presented
with metastasis to the thyroid gland after thyroidectomy. The rest of
the extension studies were negative, and she did not require adjuvant
treatment. The second case was a woman that came to the emergency
department due to urinary retention secondary to urethral metastasis
from a kidney tumor, with no metastases at other levels. The third case
was a man that presented with recurrence of papillary renal cell carcinoma
in the bladder mucosa associated with lung metastases.
Discussion: Thirty-four percent of metastases to the thyroid gland have
a renal origin. The urethra is an uncommon site for metastasis. In general,
bladder metastases from renal carcinoma have a poor prognosis,
with only 56 cases described in the literature. The treatment of choice
for resectable lesions is surgical extirpation, and anti-angiogenic therapy
is reserved for nonresectable lesions.
Conclusions: The thyroid gland, bladder, and urethra are uncommon
sites of metastases from kidney cancer. They tend to indicate advanced
disease stages and treatment is surgical extirpation in cases of resectable
lesions.
REFERENCES
Hock LM, Lynch J, Balaji KC. Increasing incidence of all stages of kidney cancer in the last 2 decades in the United States: an analysis of surveillance, epidemiology and end results program data. J Urol. 2002;167(1):57-60.
Frank I, Blute ML, Cheville JC, Lohse CM, Weaver AL, Leibovich BC, et al. A multifactorial postoperative surveillance model for patients with surgically treated clear cell renal cell carcinoma. J Urol. 2003;170(6):2225-32.
Villumsen AL, Mevik K, Fjøsne HE, Brekke MB, Haugen OA. Late onset metastases to the thyroid gland from renal carcinoma. Tidsskr Den Nor Laegeforening Tidsskr Prakt Med Ny Raekke. 2013;133(21):2262-5.
Medas F, Calò PG, Lai ML, Tuveri M, Pisano G, Nicolosi A. Renal cell carcinoma metastasis to thyroid tumor: a case report and review of the literature. J Med Case Reports. 2013;7(1):265.
Chitale SV, Burgess NA, Sethia KK, Love K, Roberts PF. Management of urethral metastasis from colorectal carcinomas. ANZ J Surg. 2004;74(10):925-7.
Tefilli MV, Stefani SD, Mariano MB. Urethral metastasis of lung carcinoma with germinative cell features. Int Braz J Urol. 2003;29(5):431-3. Available in: http://www. scielo.br/scielo.php?script=sci_abstract&pid= S1677-55382003000500008&lng=en&nrm=iso& tlng=en
Senzaki H, Okamura T, Tatsura H, Watase H. Urethral metastasis from renal cell carcinoma. Int J Urol.2003;10(12):661-3. Available in: https://onlinelibrary.wiley.com/doi/ abs/10.1046/j.1442-2042.2003.00717.x
Gelister JS, Falzon M, Crawford R, Chapple CR, Hendry WF. Urinary tract metastasis from renal carcinoma. Br J Urol.1992;69(3):250-2.
Matsumoto K, Hayakawa N, Nakamura S, Oya M. Bladder metastasis from renal cell carcinoma: retrospective analysis of 65 reported cases. Clin Exp Metastasis. 2015;32(2):135-41. Available in: http://europepmc.org/abstract/ med/25630270
Raviv S, Eggener SE, Williams DH, Garnett JE, Pins MR, Smith ND. Long-term survival after «drop metastases» of renal cell carcinoma to the bladder. Urology.2002;60(4):697.